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Chromatography Expert

Job in Bedford, Middlesex County, Massachusetts, 01730, USA
Listing for: The businesses of Merck KGaA, Darmstadt, Germany
Full Time position
Listed on 2025-12-16
Job specializations:
  • Engineering
    Process Engineer, Chemical Engineer
Salary/Wage Range or Industry Benchmark: 85300 - 187700 USD Yearly USD 85300.00 187700.00 YEAR
Job Description & How to Apply Below

Work Your Magic with us! Start your next chapter and join Millipore Sigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet.

That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

Sr. Purification Process Engineer I - MSAT

Residing in the Life Science commercial organization and based in the Burlington, Massachusetts M Lab™ Collaboration Center, the Americas MSAT group is part of a worldwide team of scientists and engineers that conducts biopharmaceutical process development, scale-up, and manufacturing support activities, known as Technical and Scientific Solutions. We work closely with our customers and our colleagues across the globe to solve the toughest problems in Life Science.

Learn more about why we love our jobs–great colleagues, a strong purpose, and having a positive impact on society–here: (Use the "Apply for this Job" box below)./3lzrhJr

Your role :

The Americas MSAT team is seeking a Purification Process Engineer to support chromatography resins, chromatography membranes, as well as associated systems and hardware. In this customer facing role, you will work closely with our clients’ development and technical teams in partnership with Millipore Sigma's Sales Managers.

  • Provide expertise to support clients with process development, scale-up, and implementation of Millipore Sigma chromatographic resin and membrane products used for bioprocess applications such as antibody, vaccine, and viral vector purification.
  • Design and execute experimental protocols to understand process sensitivity and troubleshoot operational issues with minimal supervision. Critically analyze data and model process behavior to characterize process performance or troubleshoot root cause. Clearly communicate recommendations to GMP biopharmaceutical customers.
  • Assist and train clients with resin column packing via remote consultation or on-site support.
  • Serve as key interface with Sales, R&D, Marketing, and Global MSAT colleagues to communicate Voice of the Customer and Market Trends. Keep abreast of the latest development in chromatography technologies including continuous chromatography and purification of novel modalities.
  • Proactively seek out scientific leadership opportunities in industry forums to advance the industry “state of the art”.
  • Travel requirement up to 30%

In addition, leveraging your knowledge in chromatography, you will help to guide customers with use and implementation of related chromatography hardware, single-use components, systems, and process control strategies.

Minimum Qualifications:
  • Bachelor’s of Science in Chemical Engineering or Biotechnology with 10+ year’s related experience OR Master’s of Science in Chemical Engineering with 8+ year’s related experience OR PhD in Chemical Engineering or Biotechnology with 5-7+ years’ experience.
  • 5-7+ years practical experience with downstream biologics purification in a manufacturing or process development environment, including a knowledge of scale-up, process transfer, and cGMP manufacturing.
Preferred Qualifications:
  • In depth experience with chromatography operations at pilot or manufacturing scale, including column packing, process validation, and troubleshooting operational issues.
  • An understanding bioprocess economics, as well as strong knowledge of scale-up and scale-down sizing principles.
  • A sound knowledge of process engineering fundamentals, especially fluid dynamics.
  • Ability to communicate technical concepts to colleagues and clients using excellent written and verbal communication skills.
  • Dependable, self-motivated, and able to thrive in an autonomous working environment.

Pay Range: $85,300- $187,700

Our ranges incorporate all levels and career types available within this specific role, and are derived from relevant industry market data. Should we decide to make an offer, we will consider several factors,…

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