Applications Engineer - Bioprocessing

Application Specialist, Technologist/Engineer, Liquid chromatography, Molecular biology

Our passion for science and technology is what drives our more than 64,000 employees across 66 countries to find solutions to some of today’s toughest challenges and create more sustainable ways to live.

Work Your Magic with us! Start your next chapter and join Millipore Sigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet.

That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Millipore Sigma is looking for a Bioprocessing Applications Engineer to join the Downstream Focused Modalities Applications R&D organization. This individual will take the lead to drive the hands‑on, process‑focused scientific studies to evaluate prototype and commercialized products and technologies. Centered on understanding the end users’ pain points, goals, and needs, this role will leverage continuous development of process and unit operation expertise to design and execute applications studies which provide guidance for effective process development, optimization and deployment of Millipore Sigma technologies.

This role has a focus on lentivirus manufacturing workflows, and potential to expand to other novel modalities such as AAV, novel mAbs, mRNA, pDNA, and/or peptides.

• Work on a cross‑functional team to deliver application studies using Millipore Sigma product portfolio
• Plan, set up, and execute laboratory experiments to evaluate the performance of new technologies, or new product or component prototypes for given application scenario
• Define process control strategies and design recipes and methods for optimal operation of Millipore Sigma product offerings
• Research literature and attend conferences to keep current with the bioprocessing end users’ process design targets, performance expectations, and general bioprocessing needs
• Deliver internal and external written literature and presentations evaluating product designs and/or summarizing experimental results with a focus on technical performance

This position will be based in both Burlington and Bedford, MA.This position may include domestic or international travel (5%).

• Bachelor’s degree in Chemical Engineering, Biochemical Engineering, Biochemistry or other Engineering or Science field with 5+ years of direct bioprocess development experience

• Master’s degree in Chemical Engineering, Biochemical Engineering, Biochemistry or other Engineering or Science field with 4+ years of direct bioprocess development experience

• PhD in Chemical Engineering, Biochemical Engineering, Biochemistry or other Engineering or Science field
• 2+ years of experience with setting up and executing downstream unit operations including Chromatography, normal flow filtration and Tangential Flow filtration
• 2+ years of experience in analytical methods and high throughput platforms with respect to downstream process development

• Hands on Pharmaceutical and/or Biotechnology industry experience
• Excellent problem solving & analytical skills, including data modeling, DoE, and/or statistical analysis
• Demonstrated ability to perform analytical assays using HPLC and ELISA methods
• Excellent teamwork, and facilitation…