Director​/Senior Director, Commercial Insights

Director / Senior Director, Commercial Insights

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Stoke Therapeutics (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine. Using Stoke’s proprietary approach, the company is developing antisense oligonucleotides (ASOs) to selectively restore naturally occurring protein levels. Stoke’s first medicine in development, zorevunersen, has demonstrated the potential for disease modification in patients with Dravet syndrome and is currently being evaluated in a Phase 3 study.

Stoke entered into a strategic collaboration with Biogen in 2025 to develop and commercialize zorevunersen for Dravet syndrome. Under the collaboration, Stoke retains exclusive rights for zorevunersen in the United States, Canada, and Mexico;
Biogen receives exclusive rest of world commercialization rights. Additionally, STK-002 is Stoke’s proprietary antisense oligonucleotide in clinical development for the treatment of autosomal dominant optic atrophy (ADOA). STK-002 has been granted orphan drug designation by the FDA. A Phase 1 study (OSPREY) of STK-002 in people with ADOA is now underway. The company is also conducting early research in Syngap1, a severe and rare neurodevelopmental disorder, in collaboration with Acadia Pharmaceuticals.

The Director/Sr Director, Commercial Insights will be responsible for generating and synthesizing insights from primary market research, competitive intelligence, and relevant secondary data to guide decision‑making across the organization. The role requires strong strategic thinking, the ability to turn complex and sometimes ambiguous information into clear recommendations, and excellence in influencing senior leadership. This position will report into the Vice President, Commercial Operations.

• Own the end‑to‑end design, execution, and interpretation of primary research across patient, caregiver, HCP, and payer audiences.
• Ensure insights are high‑quality, unbiased, and directly tied to strategic questions for pipeline and commercial launch activities.
• Build a structured insights roadmap aligned with key development milestones, TPP refinement, positioning, and launch planning.

• Lead Stoke’s competitive intelligence function, including landscape assessments, ongoing monitoring of clinical, regulatory, and commercial developments, and synthesis of implications.
• Deliver timely alerts, threat/opportunity assessments, and scenario planning to R&D, Commercial, Medical, and Executive Leadership.
• Partner cross‑functionally to ensure a consistent, forward‑looking understanding of the competitive environment.

• Integrate primary research, competitive intelligence, and relevant secondary data into cohesive, actionable recommendations.
• Serve as a strategic thought partner across Marketing, Commercial Operations, Clinical, Medical Affairs, and HEOR.
• Shape key strategic deliverables, including TPP refinement, brand strategy, patient journey mapping, demand drivers, and launch plans.

• Partner closely with forecasting and analytics to ensure insights inform models and commercial planning assumptions.
• Work as a bridge between internal stakeholders and external vendors to ensure clarity of objectives, quality of deliverables, and value creation.

• Manage relationships with research agencies and CI partners, ensuring best‑in‑class quality and efficient use of resources.
• Oversee annual insights budgets, project scopes, and timelines.

• Bachelor’s degree required; advanced degree (MBA, MPH, Pharm
  
  D, MS) strongly preferred.
• 10+ years of progressive experience in market research, competitive intelligence, commercial strategy, or insights generation within biopharma.
• Experience in rare disease, neuroscience, or genetic medicine preferred.
• Demonstrated success presenting insights and influencing executives and cross‑functional…