Sr Director, Program and Portfolio Management

Sr Director, Program and Portfolio Management

Join to apply for the Sr Director, Program and Portfolio Management role at Tonix Pharmaceuticals

This range is provided by Tonix Pharmaceuticals. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

$/yr - $/yr

About Tonix

Tonix is a fully integrated biotechnology company, publicly traded on NASDAQ (ticker: TNXP), with marketed products and a pipeline of development candidates The Company is focused on commercializing, developing, discovering, and licensing therapeutics to treat and prevent human disease. In August 2025, Tonix received FDA approval for Tonmya™ (cyclobenzaprine HCl sublingual tablets), a first‑in‑class, once‑daily, non‑opioid treatment for fibromyalgia. Tonmya is the first new fibromyalgia therapy approved in over 15 years, following successful Phase 3 trials demonstrating significant symptom improvement.

Commercial launch is expected in the fourth quarter of 2025. Tonix also markets Zembrace® Sym Touch® (sumatriptan injection) 3 mg and Tosymra® (sumatriptan nasal spray) 10 mg, both indicated for the treatment of acute migraine with or without aura in adults.

Tonix’s development portfolio includes product candidates in central nervous system (CNS), immunology, immuno‑oncology infectious disease and rare disease. The CNS pipeline features both small molecules and biologics to treat pain, neurologic, psychiatric, and addiction conditions. The immunology portfolio includes biologics to address organ transplant rejection, autoimmunity, and cancer. The infectious disease pipeline includes a vaccine in development to prevent smallpox and monkeypox, which also serves as a live virus vaccine platform for other infectious diseases.

Finally, the rare disease portfolio includes a product in development for Prader‑Willi syndrome, which has both orphan drug designation and rare pediatric disease designation grants from the FDA.

Tonix owns and operates a state‑of‑the‑art infectious disease research facility in Frederick, Md.

Please visit  for specifics on the pipeline.

* All of Tonix’s product candidates are investigational new drugs or biologics and have not been approved for any indication.

Tonix is looking for a full‑time Senior Director of Program and Portfolio Management (PPM) to effectively shape and implement PPM strategies decision making for a complex portfolio of drug development programs and execution of decisions. The Senior Director of PPM will be responsible for implementing portfolio management best practices, drafting strategic and operational plans, mentoring project managers (PM) and operational staff, and supporting effective communications across multiple departments  individual in this position will also be responsible for building out the team of PMs which would report into this role.

This is a fast‑paced, challenging position offering a competitive compensation and benefits package. This position will report directly to the Company’s Chief Operating Officer that will ideally be based at the Tonix Chatham, NJ office.

• Lead and manage cross‑functional teams interacting with clinical, nonclinical, regulatory, CMC, discovery, and others to set priorities, work toward goals and monitor progress of programs
• Develop portfolio tools and materials to support portfolio decision‑making
• Create, implement, and refine PPM practices to support leadership, PPM staff, and delivery of program goals
• Lead regular portfolio operations committee meetings and portfolio strategy sessions
• Coordinate and manage due diligence teams and decision making on in licensing activities for the portfolio
• Help to buildout and lead PMs responsible for developing cross‑functional program plans, timelines, and budgets in collaboration with functional area leads
• Facilitate effective, science‑based business decisions including development of scenarios and strategic impact of decisions
• Ensure all decisions are assessed as to their risks and impacts as well as accountable for communication to…