Animal Technician , Innovative Genomics Institute

Animal Technician (9611C) – Innovative Genomics Institute, UC Berkeley

Position to manage and oversee the laboratory’s mouse colony and contribute to in vivo CRISPR/Cas9 experiments, while performing advanced procedures such as surgeries, injections, flow cytometry, sequencing, and histological analysis.

UC Berkeley fosters a welcoming community built on openness, freedom, and belonging, supporting academic and research excellence, diversity, equity, and social justice.

The Innovative Genomics Institute (IGI) partners with UC San Francisco to accelerate genome discovery and translate technologies to improve human health and sustainable agriculture through CRISPR-based genome editing.

The Animal Technician (SRA III) manages the mouse colony, designs and executes in vivo CRISPR/Cas9 experiments, performs surgeries and injections, conducts flow cytometry, sequencing, and histological analysis, and coordinates laboratory budgets, safety, and training.

The First Review Date for this job is: 12/31/2025. For full consideration, please apply by 01/05/2026.

• Responsible for overseeing all operations of the lab’s mouse colony including basic animal husbandry and genotyping of mice, managing logistical amendments to animal use protocols, and ensuring the operational budget for the colony stays balanced.
• Contributes intellectually and technically to the design of animal-based experiments for in vivo CRISPR/Cas9 treatment platforms, including development of methods to deliver CRISPR systems, molecular and cellular analysis of efficacy and safety of treatments, and animal behavioral characterization during treatment.
• Oversees and coordinates the testing of genome editing-based therapeutics in mice.
• Assists and leads multiple projects, takes initiative on process improvement efforts, and contributes to a collaborative research environment.
• Consults with academic supervisors or professional researchers on the nature and objectives of the research project or instructional design goals.
• Performs precise surgeries and injections; conducts molecular (flow cytometry, sequencing, Western blotting) and histological analyses of tissue following treatment.
• Conduct animal behavioral assays.
• Manages laboratory budget and provides forecasting of future expenditure.
• Maintains research endeavors with collaborators and lab personnel to ensure project objectives and timelines are achieved.
• Ensures regulatory compliance relative to safety in small to medium or single facility; provides staff training in equipment use and safety protocols; assists with compliance paperwork.
• Assists with protocol renewals and safety inspections.
• Performs laboratory research/instruction inventory planning and purchasing.
• Lab support duties include autoclaving waste and ordering/restocking supplies.
• Ensures that specimen collections and equipment are maintained properly.
• Collects, analyzes, and presents data during regular lab team meetings.
• Contributes toward articles for publication in scientific journals or for presentations at conferences or symposiums.

• A minimum of three years of experience in an academic laboratory setting.
• Experience with sterile tissue culture techniques, PCR, basic lab maintenance duties, excellent organizational skills, and attention to detail.
• Experience with lab automation, knowledge of material and information tracking in large-scale experiments.
• Significant experience with mouse handling, coordinating breeding strategies, and genotyping transgenic mice.
• Solid interpersonal skills to develop and maintain effective working relationships with students, faculty, and staff.
• Experience performing small animal surgery and injections, including intravenous injection via tail vein.
• Experience with blood sampling.
• Experience with stereotaxic surgery for compound injection/cannula implantation.
• Experience with intraosseous (IO) infusion.
• Experience with mouse models of genetic disease; experience working with humanized mice required.
• Experience with mouse necropsy.
• Skilled in histological analysis of tissue, including immunohistochemistry.
• Skill…