Senior Manager, Tax

SENIOR MANAGER, TAX

Billerica, MA (HYBRID)

Quanterix is a global leader in ultra-sensitive biomarker detection, enabling breakthroughs in disease research, diagnostics, and drug development. Its vision is to lead the next era of precision biomarker science to power earlier detection, better decisions, and improved human health. Its mission is to make biology measurable at its most fundamental level, delivering earlier insight when it matters most. Across discovery to clinical applications, Quanterix empowers scientists and healthcare providers to improve patients' lives through detection and understanding of disease.

Its proprietary Simoa technology delivers industry-leading sensitivity, allowing researchers to detect and quantify biomarkers in blood and other fluids at concentrations far below traditional limits. With more than 3,400 peer-reviewed publications, Quanterix has been a trusted partner to the scientific community for nearly two decades. In 2025, Quanterix acquired Akoya Biosciences, The Spatial Biology Company, adding multiplexed tissue imaging with single-cell resolution to its portfolio.

Together, the combined company offers a uniquely integrated platform that connects biology across blood and tissue-advancing precision medicine from discovery to diagnostics.

We are looking for an experienced, hands-starter to serve as our tax leader. Reporting to the VP, Corporate Controller, this role is responsible for core domestic and international tax operations, including income tax compliance, indirect tax compliance, tax accounting, and related SOX controls for a growing global public company.

You will partner closely with Accounting, SEC Reporting, Treasury, Legal, FP&A, Operations, and external advisors to support timely compliance, accurate reporting, scalable processes, and business-informed tax decisions. The successful candidate is a self-starter who can take ownership of recurring tax processes and provide clear tax insights to accounting and finance leadership.

• Manage the Company's global income tax compliance processes, including U.S. federal, state, local, and international tax filings, ensuring timely, accurate, and well-supported submissions across all jurisdictions.
• Oversee quarterly and annual tax accounting and reporting under ASC 740, including review of tax provisions, effective tax rate analyses, deferred tax assets and liabilities, uncertain tax positions, and related SEC reporting disclosures.
• Review and coordinate state and local tax filings, including income, franchise, gross receipts, sales and use, property, and other indirect tax returns, ensuring timely compliance and appropriate support across relevant jurisdictions.
• Manage VAT/GST compliance across applicable jurisdictions, including review of periodic VAT returns, supporting reconciliations, payments, refund claims, and related indirect tax filings.
• Support global transfer pricing processes, including intercompany agreements, documentation, operational compliance, and coordination with external advisors.
• Lead Article 23 import VAT reporting and related indirect tax compliance processes, including coordination with logistics, customs brokers, finance, and external advisors to ensure accurate reporting, documentation, and reconciliation of import VAT positions.
• Coordinate R&D tax credit studies, Section 382 analyses, and similar work with external third-party tax advisors.

• Maintain strong tax governance, SOX controls, process documentation, and audit-ready support for tax accounting, compliance, and reporting activities in a publicly traded company environment.
• Support tax audits and inquiries, including preparation of responses to taxing authorities, coordination with external auditors and advisors, and development of clear, well-supported technical analyses.
• Manage and coordinate third-party tax advisors, including scope, deliverables, timelines, and budgets.
• Prepare and review technical tax memoranda, position papers, return-to-provision analyses, and other documentation for management, auditors, and external advisors.
• Communicate complex tax matters clearly and effectively to finance leadership and cross-functional stakeholders.

• Evaluate SALT nexus, apportionment, filing positions, credits, incentives, and exposure areas, partnering with external advisors to support compliant and efficient state and local tax reporting.
• Develop,…