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Process Development Chemist; Pharmaceutical

Job in Bloemfontein, 9300, South Africa
Listing for: Placements24
Full Time position
Listed on 2026-10-18
Job specializations:
  • Pharmaceutical
    Pharmaceutical Science/ Research, Pharmaceutical Manufacturing, Chemical Manufacturing
Job Description & How to Apply Below
Position: Process Development Chemist (Pharmaceutical)
About the Role

Our client is seeking a talented and innovative Process Development Chemist to join their manufacturing team in Bloemfontein . This role is central to optimizing and scaling up chemical synthesis processes for pharmaceutical intermediates and Active Pharmaceutical Ingredients (APIs). You will apply your expertise in organic chemistry and process engineering to develop robust, safe, and cost-effective manufacturing methods, ensuring efficient production.

This is a prime opportunity to contribute to the advancement of pharmaceutical manufacturing in the heart of the Free State, working within a supportive environment that values scientific rigor and continuous improvement.

Key Responsibilities
  • Develop, optimize, and scale-up chemical synthesis routes for pharmaceutical intermediates and APIs.
  • Conduct laboratory experiments to investigate reaction kinetics, thermodynamics, and safety parameters.
  • Identify and mitigate potential process hazards, ensuring safe operating procedures are developed.
  • Collaborate with engineering teams to ensure smooth technology transfer from lab to pilot plant and commercial scale.
  • Troubleshoot process issues and implement solutions to improve yield, purity, and efficiency.
  • Characterize materials using analytical techniques such as NMR, Mass Spectrometry, and Chromatography.
Requirements
  • PhD or Master's degree in Organic Chemistry, Process Chemistry, or Chemical Engineering.
  • Minimum of 5 years of experience in process development within the pharmaceutical or fine chemical industry.
  • Strong background in synthetic organic chemistry and reaction mechanism.
  • Experience with process scale-up, hazard evaluation, and troubleshooting manufacturing issues.
  • Proficiency with analytical techniques for chemical characterization.
  • Excellent problem-solving skills and ability to work effectively in a team.
Benefits
  • Competitive salary and performance-based incentives.
  • Comprehensive medical aid and retirement fund contributions.
  • Opportunities for professional development and specialized training.
  • A stimulating work environment focused on innovation and operational excellence.
  • Direct impact on the successful production of vital pharmaceutical compounds.
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