Assistant Scientist - AI-Enabled Immune Digital Twin & Organ Damage Mechanistic Model

Assistant Scientist - AI-Enabled Immune Digital Twin & Organ Damage Mechanistic Model

Non-Tenure Track

IU Bloomington Intelligent Systems Engineering

Bloomington

AI-Enabled Immune Digital Twin & Organ damage Mechanistic Model Scientist:
Assistant Scientist;
Biocomplexity Institute at Indiana University Bloomington (PI: Dr. James

A. Glazier)

Your primary duties will be to develop biologically meaningful,interpretable model components linking immune-state dynamics toorgan-damage risk (lung, kidney, liver) in critical illness underthe direction of Dr. James

A. Glazier. You will map clinicalbiomarkers to model states, define biological scoring criteria for digital twin ensembles, collaborate with national consortiumpartners, write technical publications, and prepare milestone-readycontract deliverables.

60% Dynamic Immune & Organ Modeling:
Develop fast,interpretableODE /network/mechanistic model modules linking immune dysfunctionto organ injury; map clinical time-series and biomarkers to modelstates; formulate biological plausibility and scoringcriteria.

40% Consortium Deliverables & Research:
Prepare test cases,model packages, and model cards; write research papers; present findings; collaborate with national consortium partners in systemsbiology and clinical data science.

• Ph.D. or equivalent terminal degree in quantitative, computational,or biomedical discipline.
• Programming proficiency in Python, Julia, R, or MATLAB ; background in mechanistic modeling ( ODE /dynamical systems, QSP, oragent-based); familiarity with inflammation, cytokine signaling,sepsis, or critical care biology.
• One year of successful postdoctoral research experience.

Please contact Professor James Glazier at glazier.

100,000/Assistant Scientist

11/02/2026

IU-