Director, Process Chemistry

For our client, we are seeking a Director, Process Chemistry to join the team of a leader in the Pharmaceuticals & Biotech space.
This leader will guide process chemistry strategy across multiple programs, supporting the advancement of small molecule drug substance development from early research through late-stage execution. The role will partner closely with cross-functional CMC stakeholders and external development partners to enable robust, scalable, and compliant delivery of clinical and commercial materials. This is a highly technical leadership position focused on process design, API form selection, and the translation of laboratory findings into practical manufacturing approaches.

Location:

Remote
Compensation: $215,000 – $235,000 annually

• Lead Process Chemistry R&D for multiple projects from early to late phase
• Design drug substance processes for early and late phases, managing progression from lab to pilot plant
• Provide chemistry and technical leadership throughout the product lifecycle
• Identify and finalize API forms to support pharmaceutical development
• Integrate closely with cross-functional CMC teams for clinical and commercial drug substance delivery
• Collaborate with and oversee external CROs and CDMOs to meet project deliverables
• Analyze data from external experiments to plan synthetic strategies

• Advanced degree in Chemistry, Pharmaceutical Sciences, Engineering, or related discipline, or equivalent experience
• 12+ years in CMC with focus on small molecule drug substance
• Familiarity with continuous processing, biocatalysis, or high-throughput experimentation is advantageous
• Strong understanding of US and EU cGMP regulations for drug substances and products
• Comprehensive knowledge of CMC development through all drug development phases
• Experience collaborating with third-party CRO / CMO partners
• Familiarity with salt/crystalline form selection and experience in oligonucleotide chemistry is a plus

• 99% premium coverage for medical, dental, and vision plans
• Company-paid life insurance, AD&D, and disability benefits
• 401(k) match dollar-for-dollar up to 6% with stock incentives
• Discretionary quarterly bonuses and flexible wellness benefits
• Generous PTO, paid holidays, and company-wide shutdowns

Our client is an equal opportunity employer.