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Manager, Product Portfolio

Job in Boston, Suffolk County, Massachusetts, 02298, USA
Listing for: Dana-Farber Cancer Institute
Full Time position
Listed on 2026-11-04
Job specializations:
  • Business
    Change Management
Salary/Wage Range or Industry Benchmark: 150000 - 171000 USD Yearly USD 150000.00 171000.00 YEAR
Job Description & How to Apply Below

Product Portfolio Manager is accountable for the strategic direction, operational performance, and continuous evolution of an integrated portfolio of products, applications, and capabilities supporting a defined business domain. The role leads and develops a team of Product Managers and Application Analysts and ensures the portfolio delivers reliable day-to-day service while advancing the capabilities, experiences, and outcomes needed by the business. As a strategic partner to business and technology leadership, the Manager translates business priorities and end-to-end process needs into a cohesive product direction, balancing operational demands with opportunities for innovation, improvement, and investment.

The role brings together product strategy, release planning, performance management, change and adoption, and cross-domain collaboration to ensure the organization realizes sustained value from its technology investments.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations.

We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Primary Duties and Responsibilities

  • Provides strategic and operational leadership for an integrated portfolio of products, applications, and capabilities supporting an assigned business domain. Translates organizational and business objectives into portfolio priorities, balancing daily operational needs with longer-term business and technology objectives. Maintains a holistic understanding of end-to-end business processes and dependencies across the domain and with other functional areas.
  • Partners with business and technology leaders to define product direction, priorities, roadmaps, and investment recommendations for the portfolio. Leads the team in evaluating new capabilities, features, enhancements, and emerging technologies based on business value, user needs, operational impact, risk, and available resources. Oversees release planning and coordinates priorities across products and teams to drive cohesive and sustainable improvements.
  • Provides oversight of the day-to-day management, health, service, and support of the domain portfolio, ensuring established quality, performance, and service expectations are met. Sets priorities for operational work, customer service, issue resolution, and continuous improvement while coordinating with other technology teams to maintain business continuity. Identifies operational risks, recurring issues, and opportunities for improvement and ensures appropriate actions are prioritized and addressed.
  • Serves as a primary relationship leader between the business and technology organizations for the assigned domain, fostering strong partnerships and effective communication. Represents business needs while balancing enterprise objectives, cross-functional dependencies, technology standards, governance, and resource constraints. Uses sound judgment to make decisions within established objectives and governance and develops recommendations for matters requiring broader leadership direction.
  • Works with Product Management leadership and business stakeholders to establish and manage KPIs that measure portfolio health, service performance, adoption,…
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