Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing

Director of Financial Planning and Analysis, Biopharmaceutical Sciences and Manufacturing Operations (BSMO)

The Director of Financial Planning and Analysis for Biopharmaceutical Sciences and Manufacturing Operations (BSMO) is a key member of Vertex’s Financial Planning & Analysis team. This role partners closely with Commercial Manufacturing and Tech Ops (CMTO) and Commercial Finance and Disease Strategy Team (DST) Finance to support our Cell and Gene Therapies portfolio, with a specific focus on CASGEVY, the first-approved CRISPR-based gene‑editing therapy used to treat Sickle Cell Disease and Transfusion‑Dependent Thalassemia.

The role has the opportunity to work across the organization by providing analysis and insights that drive key decisions around manufacturing strategy and resource allocation to optimize the profitability of CASGEVY. In addition, the position is an integral part of the BSMO Finance team and plays a key role in supporting P&L, capital and inventory budgeting, forecasting, long‑range planning, and month‑end close processes.

This position is based in our Boston, MA location (Seaport area) and requires a hybrid work schedule with 3 days in office / 2 days remote on a weekly basis.

• Partners with the External Manufacturing, Supply Chain, and Commercial functions to influence CASGEVY business operations and optimize decisions as part of the Sales and Operations Planning (S&OP) process.
• Identifies ROI/trade-off opportunities to drive profitability and support key decisions around CASGEVY manufacturing and supply chain strategy.
• Oversees the monthly/quarterly accounting close for expenses and accruals related to CASGEVY Operating Expense and COGS, including flux analysis and compliance with SOX control requirements.
• Supports analytics and transparent reporting to drive forecast accuracy and inform on key drivers of any variances to plan, with full transparency on any judgments about risks and opportunities for both operating expenses, capital expenses and COGS.
• Supports the financial planning process (annual budget, forecasts, long range plan, etc.) by providing forward‑looking observations and developing key scenarios.
• Develops and coaches team members to encourage growth and new opportunities and contributes to an atmosphere of inclusivity across the team
• Works closely with other members of the CFO organization including Commercial Finance, DST Finance, Strategic Sourcing and Accounting to maintain a continuous improvement mindset and promote strong communication, sharing of best practices and efficient processes.

• Bachelor's degree in Finance or Accounting required. MBA and/or other advanced degree preferred.
• 10+ years of relevant experience in finance managerial role, demonstrating strong technical and analytical skills and a track record of success working in a team‑based environment or the equivalent combination of education and experience.
• Experience in business partnering with Manufacturing/Supply Chain executive teams
• Proven ability to proactively manage efficient processes across Operating Expenses, Inventory and COGS, driving high‑quality inputs from the business in support of creating and managing complex budgets, forecasts, and analyses in a dynamic, fast‑paced environment.
• Deep understanding of Biotech/Pharma manufacturing finance to address a broad range of challenges and business issues across all functions with the ability to make and facilitate quick decisions
• Expert analytical and financial modeling skills to evaluate a broad range of financial questions.
• Excellent communication and presentation skills, with a proven ability to present complex financial insights to senior stakeholders.

• Strategic thinking and problem‑solving.
• Critically, this role requires an expert ability to influence without authority at the highest level and collaborate effectively in support of shared goals.
• Strong business acumen and judgment, and knowledge of the company's markets/products and industry trends.
• Expertise with Excel and PowerPoint;
  Working knowledge of Hyperion or similar enterprise planning tools.
• Exceptional…