Senior Manager, Commercial Finance Boston, Massachusetts

Ironwood Pharmaceuticals is a leading global gastrointestinal (GI) healthcare company on a mission to advance the treatment of GI diseases and redefine the standard of care for GI patients. We are pioneers in the development of LINZESS® (linaclotide), the U.S. branded prescription market leader for adults with irritable bowel syndrome with constipation or chronic idiopathic constipation. Ironwood is also advancing apraglutide, a next-generation, long-acting synthetic GLP-2 analog being developed for rare gastrointestinal diseases, including short bowel syndrome with intestinal failure.

Building upon our history of GI innovation, we keep patients at the heart of our R&D and commercialization efforts to reduce the burden of GI diseases and address significant unmet needs.

Founded in 1998, Ironwood Pharmaceuticals is headquartered in Boston, Massachusetts, and has operations in Basel, Switzerland.

The Senior Manager, Commercial Finance is a key member of the Financial Planning & Analysis group within Ironwood’s Finance Department, reporting to the Head of FP&A, and serves as a strategic finance business partner to Ironwood's Commercial function. This role leads financial planning, performance analysis, gross-to-net (“GTN”) reporting, and decision support for Ironwood's commercial business and is a key finance interface for the company’s collaboration arrangement with Abb Vie for LINZESS, a blockbuster GI brand.

This role will also lead Commercial finance efforts for any future product launches in partnership with the Commercial function. The position plays a critical role in planning and forecasting, assessing business performance, driving revenue, evaluating strategic opportunities, and providing actionable insights that influence commercial decision-making, in collaboration with commercial analytics.

The ideal candidate combines strong commercial biotech experience and understanding of pharmaceutical cash flows and contributors to gross and net sales knowledge with executive presence, strategic thinking, and the ability to translate complex financial information into clear business recommendations.

• Serve as the primary Finance business partner to the Chief Commercial Officer and Commercial organization, providing performance analysis, strategic guidance on investments, resource allocation, and business priorities.
• Lead internal forecasting from gross-to-net sales through revenue, including development of long-range assumptions, price and channel sensitivity analyses, impacts of pharmaceutical contracting, new policy impacts, and scenario-based models.
• Lead Commercial Finance processes for the Annual Operating Plan, Mid-Year Forecast, quarterly forecasts, and long-range planning, ensuring timely and aligned cross-functional inputs.
• Own quarterly Commercial financial close and reporting processes, including variance analysis, GTN reporting and reserve analysis, collaboration settlement reviews, and preparation of executive-ready review materials.
• Develop business cases, cost models, ROI analyses, and financial recommendations for commercial programs, market opportunities, and strategic initiatives.
• Serve as a key Finance representative for the Ironwood-Abb Vie collaboration for LINZESS, supporting partnership forecasts, business reviews, and strategic decision-making.
• Lead quarterly and annual Commercial reviews, analyzing business drivers, market dynamics, competitive impacts, risks, and opportunities in collaboration with commercial insights team.
• Translate complex financial and commercial results into clear, actionable recommendations and executive-level presentations for senior leadership and governance forums.
• Manage departmental budgets and expense…