Research Scientist
Listed on 2026-01-12
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Healthcare
Clinical Research -
Research/Development
Research Scientist, Clinical Research
Summary
In consultation with their Principal Investigator (PI), undertake and execute a program of scientific study culminating in publication. Drives research projects scientifically and determines the course of research as evidenced by leadership, obtaining funding, writing, or other recognition. May not necessarily receive independent resources; however, their contribution is essential to the conceptual/scientific success of the project. They assist their PI in the training and supervision of other laboratory personnel and in a wide variety of administrative tasks, as necessary.
Does this position require Patient Care? No
Essential Functions- Makes proficient intellectual contributions to scientific strategies of the group/lab and plays a leadership role by acting as subject matter authority in the field.
- Contributes to the design and execution of experiments and/or research projects.
- Exercises judgment in selecting methods and technologies to obtain results.
- May collaborate with external researchers and/or receive external project funding support.
- Presents results and prepares publications.
- May assist PI in the training and supervision of other staff.
This position in the BWH Center for Cellular Profiling offers the opportunity to join a group studying single‑cell and spatial organization in disease pathology. Our Center performs a combination of high‑dimensional analyses, including single‑cell RNA sequencing, spatial transcriptomics, and high‑dimensional flow cytometry. Under general supervision by Drs. Brenner and Wei, and in accordance with established hospital policies and procedures, the self‑motivated individual will perform activities related to the single‑cell genomics and/or flow cytometry cell sorting, including NGS library generation, 10X Genomics workflow (Chromium, Visium, and Xenium), and or familiarize with BD or Sony cell sorters and analyzers.
Responsibilities include the implementation and execution of single‑cell and novel spatial transcriptomic techniques. In addition, the candidate will supervise trainees and technicians to perform NGS and 10X Genomics pipelines. The candidate will also conduct consultation with investigators and core users, perform troubleshooting, and work with administrative directors to support budget development and planning.
- Cell capture, NGS library generation.
- Plan library sequencing strategies.
- Review sequencing data.
- Troubleshoot techniques.
- Perform cell sorting.
- Maintenance of the cell sorters and analyzers.
- Identify and resolve technical issues with flow cytometry instruments, maintaining equipment, and ensuring quality control.
Doctorate in a related field of study required.
ExperiencePrevious research experience (inclusive of graduate and postdoctoral experience) 5‑7 years required.
Knowledge, Skills, and Abilities- Excellent research skills.
- Demonstrated evidence of specific scientific competence in field.
- Demonstrated broad knowledge of field.
- Evidence of potential for scientific creativity and original thought.
- Able to exercise independent judgment and leadership.
- Ability to contribute to publications.
- Standing Frequently (34‑66%)
- Walking Frequently (34‑66%)
- Sitting Occasionally (3‑33%)
- Lifting Frequently (34‑66%) 35lbs+ (w/assisted device)
- Carrying Frequently (34‑66%) 20‑35lbs
- Pushing Occasionally (3‑33%)
- Pulling Occasionally (3‑33%)
- Climbing Rarely (
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