Director, Pain, Global Value & Access Strategy

Job Description General Summary

The Director, Pain, Global Value & Access Strategy role will serve as Market Access Lead for the chronic indications (DPN/LSR/PNP) across our Pain portfolio, with a specific focus on suzetrigine. Based on positive Phase 2 data, Vertex is advancing into pivotal development in diabetic peripheral neuropathy (DPN) and lumbosacral radiculopathy, or LSR, which is pain caused by impairment or injury to nerve roots in the area of the lumbar spine.

The individual will be responsible for leading the development of Global Market Access strategies, as well as co‑lead the Global Commercial Team across the Vertex Pain portfolio. The role reports to Sr. Director, Pain Portfolio lead.

• Responsible for Global payer strategic planning to support value and access optimization for chronic indications (DPN/LSR/PNP) for suzetrigine as well as the broader Pain portfolio
  • Lead development of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process
    • Responsible for Global payer strategic planning to support value and access optimization; lead development of Global Payer Plan which integrates value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing
  • Accountable for ensuring that payer and market access perspectives are reflected in all cross-functional strategies (e.g. commercial, product development, regulatory affairs)
  • Ensure identification and prioritization of all evidence required to capture value, support a differentiated target product profile (TPP), and ensure local pricing and access
  • Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs
  • Inform financial forecasts
  • Partner with Health Economics & Outcomes Research (HEOR), Real-World Evidence (RWE) and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement
• Co-lead the Pain Global Commercial Team, and work cross-functionally and cross-regionally to develop optimal commercial strategies
  • The Global Commercial Team facilitates development of a commercial strategy in order to maximize the lifetime value of the asset globally; is the primary hub for alignment and input into the Disease Strategy Team
  • This role should ensure collaboration and drive alignment across Global Commercial Team and leadership to integrate market access strategy and ensure resourcing for commercial success
• Support P&MA capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment
• Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly
• Collaborate closely with HEOR, International P&R, Corporate Affairs, US Market Access, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization

• Deep working knowledge of both US and ex-US healthcare systems required; experience in comparable Global role considered a plus
• Experience in leading cross-functional teams required
• Experience in specialty and/or rare disease access models preferred
• Demonstrated ability to think strategically and make sound pricing and market access recommendations
• Entrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "make things happen"
• Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support Vertex
• General experience in commercialization and drug development
• Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex
• Demonstrated relationship building at all levels of the organization and across geographies
• Recognized as a team player with excellent interpersonal skills who is flexible and reliable
• Displays sound ethics and a fit for Vertex's core values

• Bachelor's degree in relevant discipline requiring quantitative analysis; advanced degree preferred
• Typically requires 8 years of experience or the equivalent combination of education and experience

$201,200 - $301,800

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other…