Vice President, US Trade & Distribution

Mission & Core Values

Join our Mission to Protect Humankind! Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning.

Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

We guide our work with four enduring core values:

• RETHINK CONVENTION:
We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

• AIM HIGH:
We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

• LEAD WITH HEART:
Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

• MODEL EXCELLENCE:
The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Position Summary

The Vice President, US Trade & Distribution will lead the channel, trade, and distribution strategy for Vaxcyte’s portfolio, initially focused on the commercial launch of VAX-31. The emphasis will be on maximizing access and performance in retail pharmacy and Integrated Delivery Network (IDN) channels. The role will be instrumental in establishing Vaxcyte as a trusted supplier and oversee the creation of the U.S. distribution network optimizing for both the initial adult product launch and the subsequent pediatric product launch.

This executive will set the vision, strategy, and drive operational execution to ensure day one launch readiness, channel partner management, regulatory compliance, and post-launch optimization.

Position type: U.S.

-based remote role. Occasional travel required.

Essential Functions

• Strategic Leadership
- Develop and own the enterprise-wide channel, trade, and distribution strategy for the initial adult vaccine launch, ensuring alignment with brand, market access, and supply chain priorities.
- Design integrated models that balance clinical needs, commercial access, supply chain efficiency, and gross-to-net cost considerations.
- Anticipate and respond to U.S. market and regulatory trends that impact retail and IDN distribution, preparing for future pediatric launches.

• Launch Planning & Execution
- Oversee end-to-end planning and execution for the forward supply chain, including model selection, proposal development, negotiations, partner review, selection and contracting.
- Lead all logistical operations to ensure readiness, including EDI, cold chain management, inventory placement, and order-to-cash systems, ensuring they are fully developed and functional.
- Ensure day one launch readiness by meeting all regulatory requirements, securing product availability at targeted retail and IDN accounts, and implementing robust safety stock and contingency plans.

• Network and Account Management
- Establish and manage the pharmacy and distribution networks for Vaxcyte.
- Build, negotiate and manage the contractual agreements and strong working relationships with channel, trade, and distribution and pharmacy partners.
- Select, onboard, and oversee strategic partners, including RFP requirements and process management.
- Build and maintain effective relationships with distributors, retail chains and large IDNs to optimize distribution performance and patient access.
- Design, negotiate and manage Trade Policies, Authorized Distribution Agreements (ADA), and Distribution Service Agreements (DSA).
- Manage all aspects of ongoing distribution account operations, including performance reviews, launch of new programs or service offerings, and comprehensive customer relationship oversight.

• Operational & Regulatory Oversight
- Build the Trade Operations Team who will manage DSA performance, inventory levels, and Service Level fill rates, distribution data, and the underlying technology infrastructure.
- Establish systems and SOPs to ensure compliance…