Research Fellow - Chekuri Lab

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Massachusetts Eye and Ear Infirmary

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Proposes and undertakes a mentored, innovative project or challenge to develop novel techniques for Ophthalmic Treatments. Designs and performs experiments, analyzes and presents the outcome.

Education MD/PhD or equivalent

Can this role accept experience in lieu of a degree? No

Pay Range: $71,750.00 - $73,544.00/Annual

The Chekuri Lab is seeking a postdoctoral fellow to join an NIH-funded research program focused on understanding the molecular mechanisms of inherited retinal degenerative diseases and developing genetic therapies for these conditions. The project uses mouse models, retinal cell and molecular biology approaches, ocular genomics, and AAV-based strategies to study disease mechanisms and evaluate therapeutic approaches.

The postdoctoral fellow will lead a mentored research project involving in vitro and in vivo experiments, molecular and functional outcome analyses, data presentation, manuscript preparation, and collaborative project development. This position is a good fit for a candidate interested in retinal degeneration, ocular genomics, gene therapy, and translational vision research.

The lab is based at the Schepens Eye Research Institute in the Grousbeck Gene Therapy Center and has close associations with the Ocular Genomics Institute and the Department of Ophthalmology at Harvard Medical School. The fellow will be part of a highly collaborative vision research community with access to resources in retinal disease genetics, ocular gene therapy, genomics, imaging, animal models, and translational research.

Review and summarize relevant literature in retinal degeneration, ocular genomics, and gene therapy.

Design, perform, and troubleshoot in vitro and in vivo experiments.

Work with mouse models, retinal/RPE tissues, cell-based systems, and molecular biology assays.

Analyze molecular, histological, imaging, functional, and genomic data.

Maintain organized experimental records, protocols, and data files.

Meet regularly with the mentor to review progress and project milestones.

Present findings in lab meetings, seminars, conferences, and project discussions.

Contribute to manuscripts, abstracts, posters, reports, and grant-related materials.

Attend ARVO meetings, seminars, and training opportunities.

Doctoral degree (MD or PhD)

Lab setting.

Possible lifting of 10 to 20 lbs., depending on nature of chosen project(s).

All employees who have access to health information whose confidentiality is protected by the HIPAA Privacy Rule are required by the Rule to receive training so that they have an understanding and knowledge of the Privacy Rule that corresponds to their job responsibilities and of the group health plan's policies and procedures that impact on their job duties. Training on the requirements of the HIPAA Privacy Rule and the plan's health information policies and procedures under the direction of the institution's privacy officer is a pre-requisite for this position.

Employees who violate the requirements of the HIPAA Privacy Rule will be subject to discipline, up to and including termination.

This description is intended to indicate essential tasks and levels of work difficulty that will be required of positions that will be given this title. It is not intended to limit or in any way modify the right of supervisors to assign, direct, or control the work of staff members under their supervision. The use of a particular expression or illustration describing duties shall not be held to exclude other duties not mentioned but that are of similar kind or level of difficulty.

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