Executive Medical Director, Global Medical Lead; Pain

The Executive Medical Director, Global Medical Lead (GML), Pain is a critical leadership role in Global Medical,responsible for the global medical strategy and implementation and trackingofglobal activities fora designateddisease area(s).Key responsibilities include, but are not limited to,diseaseareaspecific

Integrated

Medical Plan development,includingthepublication plan,globallaunch strategy and execution, scientific leadership, external medical expert engagement, and strategicalignmentwith commercial and other cross-functional business partners. This leader will also be critical in leading post-approval evidence generation strategy in the disease area. This leader reports directly to the VP, Global Medical and is a core member of the Global Medical leadership team.

They will lead theglobal medical affairs team for the designated disease area(s) and represents

Medical Affairs in all Global strategicteamswith

Development and Commercial, including the Disease Strategy Team (DST) to drive cross-functional alignment,anticipate future needs, and contribute to Medical Affairs and Vertex’s long-term success.

• Leadthedevelopment,implementation,execution, and communication of the Integrated Medical Plans,including but not limited tomedical strategy,global tactical plan,publication,congressandpost-approval evidence generationplan,in collaboration with Clinical Development, HEOR, RWE, Medical Writing, and other internal stakeholders across Vertex

• Ensure alignment of medical strategy with organizationalobjectivesby integrating individual and disease area team goalswith Vertex and DST priorities,and the goals of cross-functional partners

• Expertlydistillsinsightsand actionable outcomesthatinformstrategy anddrive the greatest impact for Medical Affairs

• Establishes and tracks medical KPIs thatdemonstrateimpact on business and patient outcomes.

• Applies structured problem-solving and root cause analysis toidentifysolutionsand make decisions that maximize medical and business impact

• Able toidentifywhat is important and impactful to medical and the wider business,prioritize competing demands and communication to key stakeholders

• Accountable for development of theglobalDA budget, management of funds allocation, and associated tracking to ensure alignment with Medical Affairs priorities and efficient resource allocation

• Serve as product and disease area expert and primary contact point for all globaldisease area related issues with the external community and internally at Vertex

• Able toleaddevelopment of peer reviewed publications, congresspresentationsand evidence generation to shape clinical practice

• Closely follow medical developments within disease area anddisseminatenew information to transform clinical trends and emerging data into new plans

• Lead the development of global scientific communications and materials including materials for globalledsymposia, advisory boards, and training.

• Accountable for medical review of assigned brand related content and global medical content aligned with Vertex SOPs

• Represent Vertex at scientific and medical forums, including medical education forums, scientific societies, patient advocacy groups, and congresses.

• Accountable for engaging and cultivating relationships with leading global key thought leaders (TL) to gain greater understanding of thediseasearea, and insights into unmet patient needs

• Tailorscommunicationto stakeholder needs, building trust and understanding across diverse audiences.

• Deliver external presentations (advisory board meetings, symposia, other medical education meetings) to enhance the medical knowledge of pipeline and marketed…