Advisor – Cell Therapy Engineering– Lilly Gene Therapy

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first.

We’re looking for people who are determined to make life better for people around the world.

Join the rapidly expanding Lilly Gene Therapy team at Eli Lilly. We invent, characterize, and advance novel gene therapy reagents for a wide range of clinical applications, working cross-functionally across disease areas and platforms. Our goal is to deliver on the promise of gene therapy for patients worldwide.

• Design, build, and optimize CAR constructs using advanced molecular biology and protein engineering strategies.
• Oversee and perform lentiviral vector (LVV) production, packaging, and characterization to support discovery-stage programs.
• Develop and implement high-throughput workflows for construct generation, LVV production, and functional screening.
• Conduct and interpret CAR functional assays in primary immune cells, including cytotoxicity, cytokine release, and proliferation assays.
• Collaborate cross-functionally with Immunology, Oncology, Computational Biology, and Translational teams to advance cell therapy programs.
• Lead and mentor a team of associates working on molecular biology and vector biology workflows.
• Maintain detailed experimental records, analyze data, and present findings to internal stakeholders.
• Contribute to troubleshooting, process optimization, and technology development initiatives.

• Ph.D. in Molecular Biology, Cell Biology, Immunology, Biotechnology, Chemical Engineering or related scientific field OR M.S with 10+ years of relevant industry experience.

• Proven expertise in molecular biology techniques (cloning, mutagenesis, PCR/qPCR/ddPCR, sequencing).
• Hands‑on experience with CAR construct design and functional assays in primary immune cells.
• Strong background in lentiviral vector production, packaging, and characterization.
• Demonstrated ability to lead and mentor junior scientists in a laboratory setting.
• Experience with site‑directed integration technologies (e.g., CRISPR, recombinase systems).
• Familiarity with high‑throughput screening approaches and automation platforms.
• Exposure to vivo models for CAR‑T evaluation and high‑throughput in vivo screening.
• Excellent problem‑solving skills and ability to troubleshoot complex workflows.
• Strong communication and collaboration skills in a multidisciplinary environment.

• This role may require up to 10–15% travel for conferences or training.
  
  Location:
  
  15 Necco Street, Boston Seaport, MA 02210.

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Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include:
Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more…