Senior Director, Core Technology Architect

# Senior Director, Core Technology Architect Vertex Pharmaceuticals Boston, MAFull-Time Aug 08, 2026

Pharmaceutical##

Job Description
** Job Description
** Vertex is seeking a Senior Director, Solution Architect – Core Technology to serve as a senior individual contributor responsible for defining and driving an integrated architecture strategy across infrastructure and collaboration platforms in a global, GxP-regulated biopharma environment.

This leader will establish the foundational architecture function within Core Technology and partner closely with domain leaders across cloud, network, collaboration, end-user computing, workplace technology, and service management. This role will ensure that enterprise technologies are cohesive, scalable, secure, and compliant, while helping shape a unified AI and digital workplace strategy across Microsoft 365, cloud platforms, and end-user environments.

This role will partner closely with Information Security to co-architect cybersecurity capabilities across the Core Technology ecosystem and drive alignment between infrastructure, collaboration, and security architecture strategies to ensure secure, scalable, and compliant technology solutions.
** Key

Duties and Responsibilities:

** Enterprise Integration & Architecture Strategy
* Define and drive end-to-end solution architecture across Core Technology domains, including:
* Cloud platforms, with an Azure-first strategy and existing AWS footprint
* Microsoft 365 ecosystem, including Teams, Exchange, SharePoint, and Copilot enablement
* Enterprise network services, including connectivity, SD-WAN, and global infrastructure
* Data center and hybrid hosting environments
* End-user computing across Windows, Mac, and mobility
* Conference room and workplace collaboration technologies, including Zoom and Teams Rooms
* ITSM and service experience platforms, including Service Now
* Partner with Information Security to co-architect and integrate cybersecurity platforms and controls across cloud, network, workplace, collaboration, and end-user computing domains, ensuring alignment with Core Technology reference architecture, operational models, and enterprise risk requirements.
* Partner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and security architecture across the enterprise
* Create reference architectures, design standards, and integration patterns across technology domains
* Eliminate silos and ensure interoperability across Core Technology services
* Drive scalable and sustainable architectural approaches that support global business needsAI & Digital Workplace Enablement
* Lead Core Technology architecture strategy to enable enterprise AI capabilities
* Support AI enablement within:
* The Microsoft ecosystem, including Copilot, Microsoft 365, and Azure AI
* End-user productivity and collaboration platforms
* Ensure AI-related solutions are securely integrated across infrastructure layers
* Partner with Security and Data teams to align AI architecture with governance, privacy, and regulatory expectations
* Help shape a seamless and secure digital workplace experience for employees globally

Architecture Governance & Standards
* Partner with Information Security to establish shared architecture principles, technology standards, integration patterns, and governance processes that align infrastructure, collaboration, and security architectures across the enterprise
* Establish architecture governance processes, including:
* Design reviews
* Technology standards
* Exception management
* Serve as the central point of accountability for cross-domain architectural decisions
* Ensure alignment with…