Therapeutic Area Lead, DMPK & Modeling; Sr. Director

Position: Therapeutic Area Lead, DMPK & Modeling (Sr. Director)
Job Description

Objectives/

Purpose:

• The Therapeutic Area Lead in DMPK&M will have strong scientific and strategic leadership to impact broad responsibilities on the pipeline, talent, and strategy. This role will supervise and lead a team of DMPK&M project representatives and Modeling & Simulation (M&S) scientists responsible for delivering on Takeda’s research pipeline in NS, GI2, or ONC therapeutic area.

• This role is responsible for oversight on the DMPK&M strategy of the respective portfolio and ensures the execution of DMPK&M project plans, translation, and dose optimization strategies, as well as review of regulatory filings.

• This role will participate in therapeutic area-driven discussions and partner with cross-functional stakeholders to align on Takeda’s strategic framework. Key deliverables will be contributing to portfolio strategy and global business operations within DMPK&M.

• Demonstrates leadership experience in guiding talented teams and is a key member of the Global DMPK&M leadership team that drives department strategy, creates a positive and effective department culture, and strengthens partnerships across the Research and Development organizations within Takeda.

Scope:

• Leads a team of DMPK project representatives and modeling scientists who have key scientific and strategic input to research projects to enable Takeda to meet its global research goals.

• Accountable for strategic planning and scientific oversight of the discovery and development portfolio for their respective therapeutic area.

• Actively supports DMPK&M Head in strategic execution of DMPK&M Vision and Mission.

• Drives the development of organizational culture and capabilities by building strong alliances across the Research and Development organizations within Takeda.

Scientific responsibilities:

• Provides scientific leadership and strategic guidance on stage-appropriate questions related to DMPK&M to ensure the selection and development of clinical candidates with optimal drug development characteristics.

• Builds and enhances an external network to keep a pulse on scientific developments, novel strategies, partnership opportunities, and the latest competitive and regulatory landscape, particularly in relation to specific therapeutic areas.

• Advises, reviews, and approves, on behalf of DMPK&M, milestone presentations and PRC narratives. Oversees and participates in regulatory activities, including the review and approval of robust and fit-for-purpose submission packages in their respective areas.

Strategic responsibilities:

• Act as the DMPK&M functional representative in governance committees and discussions regarding prioritization, strategy, resources, timelines, and decision-making criteria.

• As the DMPK&M Therapeutic Area Lead, this role will facilitate the alignment of DMPK&M strategy with DDU and TAU portfolio goals.

• Collaborate with DDU and TAU senior leaders, communicating needs, strategy, and execution plans, while consulting with DMPK leadership to ensure resources and goals are aligned.

• Accountable for appropriate resourcing of project support by collaborating with the Global DMPK&M leadership team.

• Resources and reviews in-licensing evaluations for their respective therapeutic area.

Management responsibilities:

• Actively attract, develop, and retain talent.

Dimensions and Aspects:

Technical/Functional (Line) Expertise:

• Comprehensive understanding of drug discovery and development, the pharmaceutical industry, DMPK&M science.

Leadership:

• Achieves success for Takeda by collaboratively working with partners across the organization.

• Ability to work across functions, regions, and cultures.

• Functional level leadership with the ability to inspire, motivate and drive results.

• Excellent communicator can persuasively convey both ideas and data, verbally and in writing.

• Proven skills as an effective team player who can engender credibility and confidence within and outside the company.

• Ability to distill complex issues and ideas down to simple comprehensible terms.

• Demonstrates leadership presence and confidence.

• Embraces and demonstrates a diversity and inclusion mindset and role models these…