Research Senior Scientist, Lead Profiling

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At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on three therapeutic areas and other targeted investments, we push the boundaries of what is possible to bring life-changing therapies to patients worldwide.

Takeda’s Lead Profiling team is building a new team of experienced, innovative, and collaborative researchers to partner with the Gastrointestinal and Inflammation (GI2) Drug Discovery Unit to design and run high throughput automated assays on state-of-the-art robotic platforms to drive an industry-leading portfolio of drugs for various gastrointestinal, autoimmune, and inflammatory diseases with high unmet medical needs. We seek a skilled Research Sr.

Scientist to join our Lead Profiling and cross-functional discovery teams.

• Design and execute pre-clinical pharmacology strategies on fully automated robotic platforms to support candidate selection, accelerating clinical translation of impactful therapties for patients with inflammatory and autoimmune disorders
• Provide deep scientific expertise in the design and execution of miniaturized, high throughput assays for immunology/cellular pharmacology, acting as a subject matter expert across cross‑functional teams
• Leverage state-of-the-art automation to streamline complex biology screening workflows and manage data across GI2 programs, in close collaboration with Takeda scientists and external partners

• Develop and implement fully‑automated screening workflows to support multiple programs in the GI2 portfolio
• Champion scientific integrity and rigor in data analysis, preparation, and interpretation of detailed protocols/SOPs.
• Collaborate effectively within a matrixed structure, clearly communicate results, challenges, and impact through presentations and discussions with broad audiences. Integrate data from cross‑functional teams to drive decision‑making.
• Think independently and creatively to explore novel drug discovery approaches to create therapies for patients suffering from immune driven disorders.

• Expected:
  PhD degree in immunology/pharmacology with 2+ years industry experience, or MS with 8+ years’ experience, or BS with 10+ years of relevant experience in pharmaceutical/ biotech R&D.
• Strong expertise and depth of knowledge in complex cell‑based assay development and screening technologies (e.g., Flow cytometry, Alpha
  
  LISA, TR‑FRET, ELISA and etc).
• Extensive experience with state‑of‑the‑art automation and assay miniaturization to streamline assay workflows.
• Significant experience leveraging high throughput data analysis platforms and LIMS systems for automated data analysis, QC and reporting.
• Foundational knowledge in engineering and programming is highly desirable.
• Proven experience in developing and/or evaluating novel small molecule and biologics.
• Stays current with emerging scientific literature, competitive landscapes, and innovative technologies.

The position will be based in Cambridge, MA. This position is currently classified as “hybrid” by Takeda’s Hybrid and Remote Work policy.

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

Boston, MA

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The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education…