Senior Director, Pharmacokinetics, Dynamics, Metabolism and Bioanalysis, Protein Therapeutics

## Senior Director, Pharmacokinetics, Dynamics, Metabolism and Bioanalysis, Protein Therapeutics Apply remote type:
Not Applicable locations:
USA
- Massachusetts
- Boston (MA Parcel B Laboratory) time type:
Full time posted on:
Posted Todaytime left to apply:
End Date:
July 20, 2026 (27 days left to apply) job requisition :
R403420
** Job Description
** At our Company, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough. Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility and scientific acumen of our team. We are creating an organization that is inspired by invention and founded on a culture of respect and collaboration.

At our Company's Research Labs Boston, you’ll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

The Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) group is seeking a dynamic, strategic thinking and collaborative Senior Director to contribute to our Company's protein therapeutic efforts from discovery through to candidate selection and into FIH trials.  This position will be based at our research labs in Boston, MA.  This senior leader will provide scientific and operational oversight for PK/PD and bioanalytical activities related to protein therapeutic drug candidates, including bispecific antibodies, antibody-drug conjugates (ADCs), fusion proteins, and emerging modalities.

The successful candidate will lead a group of principal investigators and subject matter experts and will be expected to collaborate cross-functionally with discovery biologics, nonclinical drug safety, translational medicine and therapeutic area colleagues to ensure robust program strategies from early discovery through to IND submission and beyond.  Modality and therapeutic area support will focus on protein therapeutics in our immunology and oncology portfolios, with the potential to contribute other modalities across multiple therapeutic areas.
** In this exciting position, your primary roles will include:
*** Oversee the design and interpretation of pharmacokinetic, immunogenicity and ADME studies for protein therapeutics across multiple disease indications and therapeutic areas
* Mentor and manage a team of high performing PDMB scientists and managers (multi-tiered organization) supporting protein therapeutic optimization (PK, distribution, translational strategy) and discovery bioanalytics (ligand binding assays, mass spectrometry)
* Design, implementation and analysis of in vitro and in vivo studies to understand the impact of drug disposition on disease biology, pharmacological response (PK/PD) and safety
* Contribute to global PDMB strategy through close collaboration with project teams in Boston (MA), South San Francisco (CA) and West Point (PA) focusing on building highly efficient strategies to identify and optimize protein therapeutic drug candidates
** Education Minimum Requirement
*** Ph.D (with 7+ years relevant experience) degree in biochemistry, pharmacology, pharmaceutical sciences, protein engineering, molecular biology, bioengineering, or related STEM field;
Relevant experience that includes a record of increasing responsibility and independence in a similar industrial/academic setting
** Required Experience and Skills
*** Demonstrated experience leading protein therapeutic discovery efforts as a group leader or independent project-team representative within a highly collaborative environment
* Strong understanding of protein therapeutic bioanalytical, ADME, FcRn…