Senior Principal Scientist, Quantitative Biosciences
Listed on 2026-10-11
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Research/Development
Research Scientist, Pharmaceutical Science/ Research, Drug Discovery
We are seeking a Senior Principal Scientist to provide scientific and strategic leadership for mass spectrometry-enabled discovery within the Quantitative Biosciences group in Boston. This role will help shape the application of mass spectrometry and quantitative pharmacology across discovery programs, strengthen experimental decision-making, and advance high-impact science through close partnership with local and global teams.
Job DescriptionSenior Principal Scientist
- Boston, MA
We are seeking a Senior Principal Scientist to provide scientific and strategic leadership for mass spectrometry-enabled discovery within the Quantitative Biosciences group in Boston. This role will help shape the application of mass spectrometry and quantitative pharmacology across discovery programs, strengthen experimental decision-making, and advance high-impact science through close partnership with local and global teams.
As a senior scientific leader in Quantitative Biosciences, you will lead the Boston mass spectrometry capability supporting in vitro and in vivo pharmacology, advise multidisciplinary project teams, and influence broader QB strategy. The successful candidate will combine deep technical expertise in mass spectrometry-based assay development with strong pharmacology insight, sound scientific judgment, and the ability to mentor scientists and drive cross-functional alignment.
InThis Role, You Will
- Lead the Boston mass spectrometry group in support of in vitro and in vivo pharmacology needs and serve as a key scientific partner to discovery teams across QB.
- Shape strategy for mass spectrometry-enabled assay development, experimental design, data interpretation, and quantitative pharmacology applications across discovery programs.
- Partner with multidisciplinary project teams to develop and execute mass spectrometry-based assays that inform mechanism, potency, selectivity, exposure-response, and translational decision-making.
- Provide scientific guidance to bench scientists and project teams, supporting assay selection, study design, mechanistic interpretation, and data-driven recommendations.
- Build and strengthen connections across the local Boston team and
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