Heme, Research Fellow
Job in
Boston, Suffolk County, Massachusetts, 02298, USA
Listed on 2026-10-12
Listing for:
Vertex Pharmaceuticals LLC
Full Time
position Listed on 2026-10-12
Job specializations:
-
Research/Development
Pharmaceutical Science/ Research, Research Scientist, Drug Discovery
Job Description & How to Apply Below
Lead drug discovery and translational research for in vivo gene editing therapies targeting hemoglobinopathies, with responsibilities spanning target selection, preclinical, IND-enabling studies, and Phase 1/2 trials. Responsibilities include shaping scientific strategy, guiding in vitro/ex vivo/in vivo studies, supporting target and candidate optimization, and leading cross-functional teams toward development candidate nomination.
Requirements- MD and/or PhD with 11+ years in academic, biotech, or pharma research, expertise in drug development, translational science, and disease biology, with experience in cell/gene therapy and genome editing.
- Direct hemoglobinopathy experience (e.g., sickle cell, thalassemia), familiarity with delivery systems, editing efficiency, HSC biology, regulatory pathways (FDA/EMA), and GCP.
- Hemoglobinopathies, gene editing, in vivo pharmacology, IND-enabling programs, clinical translation, and leadership in matrixed environments.
On-site, five days/week, with ad hoc flexibility.
Are you ready to take on the Heme, Research Fellow role at Vertex Pharmaceuticals LLC?
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