GRNA Process Development Scientist

Scientific and Research Fellow, Molecular biology, Liquid chromatography

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

Eurofins believes it is a global leader in food, environmental, pharmaceutical and cosmetics products testing and in agroscience CRO services. It is also one of the global independent market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, CDMO, advanced material sciences and in the support of clinical studies.

In over 35 years, Eurofins has grown from one laboratory in Nantes, France to 61,000 staff across a decentralised and entrepreneurial network of ca. 900 laboratories in 61 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2025, Eurofins generated total revenues of EUR 7.296 billion, and has been among the best performing stocks in Europe over the past 20 years.

We are seeking a process development scientist to join the guide-RNA (gRNA) process development team. The successful candidate will be contributing to gRNA drug substance process development for programs in clinical development. In this role, the candidate will synthesize, purify, and characterize gRNAs in an effort to develop drug substance manufacturing processes and controls.

• Execute solid-phase synthesis and purification experiments to support process development, scale-up, and transfer of oligonucleotide drug substance manufacturing.
• Execute routine analytics including HPLC and UV-Vis.
• Prepare buffers, reagents, and stock solutions used for process development activities, following established recipes and SOPs.
• Compile and present data to team members and key stakeholders
• Maintain an updated lab notebook, order materials, maintain lab equipment, and support equipment troubleshooting as needed.
• Uphold lab safety to the highest level of standards.

• B.S./M.S. degree in chemistry, chemical engineering, or biochemistry (or related field) with at least 2years of relevant laboratory industry experience
• Experience with oligonucleotide synthesis and purification equipment (experience with gRNA or longmer synthesis and purification development is a plus)
• Experience operating analytical equipment such as Akta chromatography systems, Agilent U/HPLC, gel electrophoresis, and Nano Drop.
• Experience with Tangital Flow Filtration (TFF) is required.
• Ability to follow established SOPs for routine analytical support.
• Experience with good documentation practices and electronic lab notebooks such as Benchling.
• Unwavering commitment to safety protocols and procedures.
• Strong attention to detail, organizational, and time-management skills.
• Effective communication skills for collaborating with team members and conveying technical information clearly.
• Strong problem-solving abilities and critical thinking skills.
• Inquisitive, analytical, laboratory technique familiarity, enthusiasm to learn and contribute in a fast-paced environment.

• Background in CRISPR gRNA development.
• Authorization to work in the United States indefinitely without restriction or sponsorship.

The position is
full-time, Monday-Friday, 8am-5pm
with overtime as needed.

Candidates living within a commutable distance of
Boston, MA
are encouraged to apply.

• Comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Eligibility for yearly goal-based bonus & merit-based increases
• Compensation:$32.00-$41.00 per hour

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.