Co-Op , In Silico Modeling

Kickstart Your Career at Vertex! Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you'll work on meaningful projects, collaborate with talented teams, and learn from industry leaders.

We're passionate about innovation, inclusion, and supporting your growth-inside and outside the lab.

• Real Projects: You'll work on assignments that make a real impact, not just busy work.
• Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career.
• Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing.
• Inclusive Culture: Collaboration and inclusion are embedded in everything we do.
• Career Launchpad: Build skills, explore career paths, and get guidance for your future career.

The Vertex In Silico Modeling Co-Op is a 6-month experiential training program for students currently working towards an advanced degree in Computational Chemistry, Computational Biology or other related fields. If you are passionate, collaborative, and growth-minded, a co-op at Vertex will help you gain meaningful experience in our Analytical Development functional areas and serve as a launchpad for your career.

The Final date to receive applications for this co-op is November 15th. Please note that Vertex reviews applications on a rolling basis and reserves the right to close this job posting prior to the listed deadline. Applicants can expect to receive an update about their application before or shortly after the Final date to receive applications.

We are seeking a highly motivated Co-Op to join our group, focusing on developing in silico modeling tools to understand structure function relationship for biologics therapeutics. As a Co-Op at Vertex Pharmaceuticals, you will have the unique opportunity to gain practical experience and contribute to meaningful projects.

This co-op role is designed to provide you with exposure to various aspects of therapeutics development, helping you build valuable skills while working alongside experienced professionals in a dynamic and innovative biopharmaceutical environment.

• Build workflows for protein structure prediction and contribute on protein structure-function relationship understanding
• Utilize molecular dynamics simulation tools to evaluate protein-protein and protein-excipient interactions, predict macroscopic properties such as aggregation propensity, protein solution viscosity, and
• Leverage experimental data to further refine the model and workflows
• Evaluate Vertex pipeline molecules with established workflows as needed
• Report on project progress, write analytical development protocols and method development reports.
• Maintain excellent written documentation (e.g. lab notebook and test forms)

• Ph.D. candidate or highly experienced Master's student studying, Computational Sciences, Biology, Chemistry or a related field
• Hands-on experience with in silico modeling and structural prediction of proteins and antibodies
• Hands-on experience with molecular dynamics simulation and understanding of protein-ligand and protein-protein interaction
• Ability to adapt and be flexible with respect to working schedule
• Excellent communication skills with the proven ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team
• Familiar with modeling tools such as: MOE, Maestro/Schrodinger, Desmond, GROMACS, NAMD/VMD
• Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships/co-ops or entry level roles within this part of the organization.
• You must be enrolled in an advanced degree program if graduating before May 2027
• You must be available to work full-time, 40 hours per week from January
  - July 2027

• Full-time, paid co-op $33.00 - 50.00 USD/hour
• Program Dates:
  January
  - July 2027
• Final date to receive applications:
  November 15th, 2026

$0 - $0

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