Senior Scientist

The Chowdhury lab and Center for BRCA and Related Genes at DFCI are seeking applicants for a Scientist position. The applicant will develop and implement next-generation sequencing (NGS) workflows to advance our fundamental knowledge of genome instability in the context of HR-deficient cancers and translate these findings into novel therapeutic applications. Collaborations and projects involve direct interaction with academic and biopharma industry partners.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations.

We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations.

We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

Job Description

Responsibilities will include, but not be limited to:

• Execute and supervise NGS projects within the Center for BRCA and Related Genes, including quality controls, protocol optimization, troubleshooting, and data analysis and interpretation.
• Provide expertise in widely used and customized NGS assays and technologies.
• Collaborate with the Center Directors and other Research Scientists and interact with investigators and scientific and technical staff within the Center.
• Interact with external/industry collaborators.
• Contribute to the preparation of manuscripts and grant applications.
• Present data at scientific meetings as needed.

The Scientist will supervise technical assistants.

• Ph.D. or equivalent degree in Molecular Biology or Genetics, with a minimum of 2 years of postdoctoral experience.
• Must have hands-on experience in next-generation sequencing (NGS) technologies and genomics, with a proven track record of publications in peer reviewed journals. A background in the field of genome stability and DNA repair is a strong plus.
• Proven experience developing and optimizing NGS workflows.
• Hands-on experience in NGS data analysis and visualization, with expertise in bioinformatics tools such as R, Python, and command-line interfaces.
• Hands-on experience operating multiple different NGS instruments.
• Demonstrated leadership and mentorship skills.
• Strong communication skills, with experience in preparing manuscripts and grant applications, and presenting research findings at scientific meetings.

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we.

If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

The hiring range is based on market pay structures, with individual salaries…