Research Lab Tech - Lagier-Tourenne Lab

The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

The laboratory is seeking a motivated individual to join our efforts in exploring disease mechanisms and developing therapeutic strategies for amyotrophic lateral sclerosis and dementia. Under the minimal supervision of the Principal Investigator and other researchers of the team, the incumbent will contribute to multiple organizational aspects of the laboratory that include ordering common laboratory supplies, general maintenance of equipment, establishment of procedures to comply with health and safety regulations and development of protocols and SOPs.

The incumbent will participate to the research activity of the lab and is expected to be fully engaged in the scientific projects, as well as participate to the scientific lab meetings. They will perform laboratory experiments which include DNA and RNA purification, quantitative PCR, gel electrophoresis, Western blots, DNA cloning, immunostaining, high throughput sequencing, CRISPR/Cas9 editing, lentiviral and mammalian cell cultures including iPSC‑derived neurons.

Experience in mouse handling and mouse histology is preferred but not necessary. They will be responsible for the analysis of the results and participate in the preparation of manuscripts. The individual must pay attention to details, work independently under minimal supervision, possess good verbal and written communication skills, and work well as part of a team. There is flexibility to hire at the Tech I or II level based on an individual's experience and skillset.

Responsible for maintaining laboratory equipment, organizing and preparing samples, conducting experiments, and recording and analyzing data. Candidates who are in the process of completing their bachelor's degree have a grace period of six months from their hire date (up to 1 year if starting per diem) to provide degree equivalency verification.

• Perform laboratory experiments following established protocols and procedures.
• Prepare and handle samples, reagents, and solutions, ensuring accuracy and adherence to safety guidelines.
• Operate and maintain laboratory equipment and instruments, conducting routine calibration and troubleshooting as needed.
• Record experimental data accurately and maintain organized records of procedures, protocols, and results.
• Compile and analyze data using appropriate statistical and analytical methods.
• Assist in data interpretation and presentation, contributing to research findings and reports.

Education:

Bachelor's Degree Related Field of Study required. Can this role accept experience in lieu of a degree? Yes. Licenses and Credentials:
Experience prior laboratory experience, either through academic coursework, internships, or employment, 1-2 years preferred.

• Strong theoretical and practical knowledge of laboratory techniques and procedures.
• Familiarity with common laboratory equipment and instruments used in research experiments.
• Proficiency in data collection, analysis, and scientific software tools.
• Excellent attention to detail, organizational skills, and the ability to multitask and prioritize tasks effectively.
• Strong problem‑solving skills and the ability to troubleshoot technical issues.
• Excellent…