Engineer, Research Scientist

Location:

Boston, MA

Duration: 12+ Months

• Support the design, manufacturing and characterization of lipid nanoparticles (LNPs) for screening critical process parameters (CPPs) and critical material attributes (CMAs) that impact critical quality attributes (CQAs).
• Support the design and execution of a wide range of experiments including DoEs to advance LNP technology and process development.
• Participate in defining equipment specification/selection, draft procedures and recommended operating parameters/ranges
• Write protocols, perform experiments, organize and analyze data, interpret results, record experiments in an electronic lab notebook, and summarize work in presentations and technical reports
• Assist in ordering supplies, making reagents, and maintaining a safe and high-performing laboratory
• Multi-task across several projects and manage time effectively to achieve results
• Collaborate with multiple cross-functional teams and execute other duties as assigned

Engineer, Formulation Sciences

We are seeking an Engineer to join our Formulation Sciences team focused on lipid nanoparticle (LNP) discovery and development for Verve’s Client CRISPR-based gene editing therapies. The successful candidate will be responsible for supporting LNP process development, scale-up, and characterization working as part of a multidisciplinary fast-paced team environment. The ideal candidate will have some process development industry experience with a desire to contribute to a team focused on championing nanomedicinal products and developing manufacturing solutions based on strong scientific principles.

• Bachelor’s/Master’s degree in chemical engineering, bioengineering, chemistry, pharmaceutical sciences, or another related field with 2+ years of relevant industry experience.
• Experience with lipid nanoparticle formulations and analytical characterization methods (Preferred)
• Strong problem-solving skills, and creative/innovative approach in problem solving.
• Ability to work independently and in very dynamic interdisciplinary team environments. Proven record in working with partners/collaborators is desirable.
• Organized, detail-oriented, and innovative self-starter who continuously seeks to improve existing laboratory methods and processes.
• Effective verbal and written communication skills; proficiency in literature search and relevant computer software skills are required.
• Knowledge of practices and equipment used to run manufacturing processes in a GMP environment, including TFF, sterile filtration, single-use technology, and sterile/aseptic processing preferred.