Senior Manager, IT Service Desk

Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA;

IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.

Position Overview The Senior Manager, IT Service Desk owns end-to-end delivery of IT support services across the organization from ticket intake through resolution, and is accountable for the people, processes, and partner relationships that keep employees and lab operations productive. This role blends hands-on service management with strategic planning: designing coverage models, managing SLAs, overseeing an MSP relationship, and driving self-service adoption, while also owning device lifecycle management and specialized support for lab and scientific systems.  

This is a working manager role. You'll set strategy and represent the service desk to stakeholders, while staying close enough to daily operations to catch quality issues, unblock your team, and support escalations when needed.  Responsibilities Service Desk Delivery Monitoring and Management  Lead a growing internal service desk team and a managed service provider (MSP) to deliver end-to-end incident and request management across all IT services, from ticket intake through closure.  

Hire, coach, and develop the team; set goals, assign work, manage performance, and balance workload between internal staff and the MSP.  Design, document, and continuously improve service desk processes ensuring consistent execution by internal staff and MSP resources.  Define service metrics and KPIs (e.g., SLA attainment, MTTR, MTTF, first-contact resolution, backlog aging, CSAT) and own the dashboards and leadership summaries used to communicate performance.  

Lead the design and delivery of self-service capabilities, including knowledge base content standards, catalog offerings, and report on ticket deflection and knowledge usage.  Define requirements for Service Now/ITSM workflow, automation, and reporting enhancements that improve service desk delivery and measurement.  Support MSP partnership success through defining scope and service levels, own runbooks and training, conduct ticket quality audits, and lead monthly/quarterly performance and SLA reviews with remediation plans.  

Onboarding, Offboarding, and Employee Lifecycle Support  Design and manage the onboarding process for account and hardware provisioning, coordinating team and MSP delivery against defined lead times, and partner with HR on new employee onboarding plans.  Own the offboarding process (device retrieval, access disablement, data preservation/handoff per HR and Legal requirements, and license reclamation) and report on completion timeliness and compliance.  

Manage the process for transfers, role changes, and contractor/vendor accounts, including periodic reconciliation against HR records and reporting of exceptions.  Physical Device Lifecycle Management (partnering with Endpoint Engineering on management tooling)  Design and manage the full hardware lifecycle process (acquire, receive, inventory, tag, provision, repair, refresh, retire, dispose), with execution delivered by the team and MSP.  Govern asset record accuracy in Service Now;

define the reconciliation cadence against physical inventory and CMDB data and report on accuracy and variances.  Maintain the standard hardware catalog and refresh cycle; set and monitor spare and hot-swap stock levels per site.  Own secure disposal and data sanitization processes, including certificates of destruction, e-waste vendor management, and audit-ready documentation.  Manage shipping and logistics processes for remote and field personnel, including return kits, and track fulfillment and return rates.  

Lab and Scientific Systems Support  Manage lab system device lifecycle processes (implement, maintain, retire) in partnership with Endpoint Engineering.  Define priority and response targets for lab incidents and…