Regional Sales Director; Western Region

Karius is a life science, venture-backed metagenomics company, focused on elevating patient care through microbial insights. We are committed to advancing diagnostics science and technology to optimize the diagnosis and treatment of infectious diseases. Through the use of genomics and AI, we are driven to improve the diagnostics landscape for infectious diseases. Karius delivers unprecedented diagnostic insight by detecting microbial cell-free DNA circulating in the body to assist physicians to make rapid treatment decisions.

This represents an incredible opportunity to join a growing life sciences company poised to revolutionize the Infectious Disease diagnostics market. We are expanding the launch of our proprietary, Next
- Generation Sequencing test in hospitals and health systems across the U.S. Joining Karius in our commercialization effort will both accelerate your career and advance our vision to see a world where infectious disease is no longer a major threat to human health.

The Regional Sales Director is responsible for achieving assigned regional revenue goals by driving sustained growth in Karius test utilization and market penetration in hospitals and across health systems with a rapidly expanding diagnostic portfolio. The RSD hires, develops, and leads a high-performing team of Clinical Sales Managers (CSMs), sets clear expectations, builds territory strategies, and fosters a culture of accountability, coaching, and continuous development.

In close partnership with Medical Science Liaison Directors, the RSD ensures coordinated and strategic customer engagement across CSM-MSL territory pairs to accelerate adoption and deepen account value.

As a key member of the Sales Leadership Team, the RSD contributes to the design and execution of national commercial strategy, champions major initiatives including new product launches, workflow/EHR integration, market development and provides timely customer insights that shape future innovation and operational excellence. This is an exciting and pivotal time to lead regional efforts at Karius as we bring transformative technologies to clinicians and patients.

Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients.

Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale.

Reports to: Vice-President of Sales and MSLs

Territory: Western Region of the United States. Preferred base location in San Francisco, Los Angeles, Seattle, Salt Lake City, or Denver, located near a major airport hub

• Achieve assigned regional revenue goals through sustained growth in both existing and new accounts.
• Drive disciplined regional execution by setting clear expectations, building territory and account development plans, and ensuring consistent adoption of the Karius Sales Cycle, KPIs, and CRM processes.
• Develop and execute regional business plans, manage regional budgets, and maintain ownership of initiatives, timelines, and performance milestones.
• Leverage sales reports and commercial analytics to guide regional priorities, inform decision-making, and ensure accurate and effective use of data across the team.
• Prepare and deliver Regional Quarterly Business Reviews (QBRs) with clear strategy, performance analysis, action plans, and resource needs.

• Hire, lead, and develop a high-performing team of Clinical Sales Managers (CSMs). Conduct regular field coaching sessions and performance reviews, using leading and lagging indicators (call activity, specialty mix, product penetration, funnel progression, account adoption) to drive continuous improvement and accountability.
• Partner closely with the Medical Science…