Contractor, Drug Metabolism and Pharmacokinetics; DMPK

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose:
Extending life's moments for children and adults living with a rare disease.

At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.

Visit our website to learn more about our company and culture! Site:

The Contractor, Drug Metabolism and Pharmacokinetics (DMPK) plans and performs in vitro and in vivo metabolism/bioanalysis assays in support of DMPK studies in discovery and early development.

The Contractor, DMPK interprets data and communicates experimental results to his/her supervisor and colleagues.

The incumbent works cross-functionally with internal departments, and external resources as appropriate, as part of PTC's discovery science project teams.

The Contractor, DMPK supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.

Primary duties/responsibilities:

• With guidance, initiates and executes scientific research and experiments and interprets and communicates results as part of multi-disciplinary team(s).
• Performs and maintains established in vitro and in vivo metabolism/bioanalysis assays.
• With guidance, develops new, and improves upon existing DMPK assays.
• Performs hands‑on in vitro and in vivo metabolism/bioanalysis assays using LC-MS/MS.
• Documents experiment details in lab books, records results in database and prepares study reports.
• Abides by all safety and regulatory guidelines.
• Performs other tasks and assignments as needed or specified by management.
• Contributes to general lab needs such as:
• Equipment maintenance and/or troubleshooting.
• Capital equipment purchases.

* Minimum level of education and years of relevant work experience.

* Special knowledge or skills needed and/or licenses or certificates required.

• A Master's degree in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or other related scientific discipline and a minimum of 2 years of relevant and progressively responsible experience in a pharmaceutical, biotechnology or similar environment OR a Bachelor's degree in these same disciplines and a minimum of 4 years of the same experience.

* Special knowledge or skills and/or licenses or certificates preferred.

• Knowledge of drug metabolism and pharmacokinetics in discovery preclinical research.

* Travel requirements

• Up to 5%
• Office/Laboratory based position

Expected Hourly Range:

$45-$70/hour. The hourly salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity.

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.