Head of Global Manufacturing Science & Technology

Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR‑T), T-cell receptor (TCR‑T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases.

From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting‑edge therapies for patients worldwide.

Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.

The Head of Global Manufacturing Science & Technology (MSAT) is the enterprise technical leader responsible for ensuring the robustness, scalability, capability, and continuous improvement of manufacturing processes across the product lifecycle. The role establishes the global MSAT strategy and provides technical leadership from late-stage development and technology transfer through commercial manufacturing and lifecycle management. The Head of Global Manufacturing Science & Technology ensures that manufacturing processes are scientifically understood, technically capable, operationally robust, scalable, and continuously improved to support reliable supply, product quality, patient needs, and business growth.

As the enterprise technical authority for manufacturing processes, the Head of Global Manufacturing Science & Technology drives process robustness, technology transfer, process validation, continued process verification, technical investigations, manufacturing optimization, and advanced manufacturing capabilities across the global network. The incumbent will be a member of the GMS Leadership Team.

• Define and execute the global MSAT strategy and operating model aligned with business, portfolio, and manufacturing priorities.
• Establish global technical standards, capabilities, and governance for manufacturing processes across internal and external sites.
• Serve as the senior technical authority for process capability, robustness, scalability, and manufacturing performance.

• Own the technical strategy for process characterization, validation, process capability, continued process verification, and process monitoring.
• Drive consistency and systematic improvement of manufacturing processes to increase yield, reliability, capacity, throughput, consistency, and cost efficiency.
• Provide technical leadership for manufacturing investigations, process deviations, and recurring performance issues.
• Establish science‑ and data-based approaches to identify process risks and proactively improve manufacturing performance.

• Provide MSAT leadership for technology transfer and manufacturing readiness from development into commercial operations.
• Ensure effective transfer of process knowledge, control strategies, technical standards, and manufacturing capabilities into internal and external manufacturing networks.
• Partner with CMC and R&D to ensure development programs are designed for commercial scalability, manufacturability, and process robustness.
• Provide technical input to major manufacturing network,…