Senior Project Manager

Job title: Senior Project Manager
Reporting to: Head of Operations
Department: Project Management
No of Direct reports: No direct reports (at appointment)
Location: Bristol

Summary: eXmoor Pharma is the only integrated cell and gene therapy CDMO with over 20 years of consultancy expertise embedded across every stage of the CMC journey — from early‑phase strategy to process development, GMP manufacturing and commercialisation. We provide comprehensive support across Viral Vectors, Autologous and Allogeneic Cell Therapies, and RNA technologies. This integrated model enables seamless progression from early‑phase strategy through to commercial readiness.

The Senior Project Manager is a critical delivery role within eXmoors growing Project Management function. The role holder will lead complex client programmes from initiation through to successful completion or ongoing commercial supply, acting as the primary interface between clients and internal cross‑functional teams. The successful candidate will bring deep biopharmaceutical project management experience and be able to demonstrate their ability to operate effectively and ensure projects meet quality, regulatory timeline and budget expectations.

This is an exciting opportunity to work with eXmoor’s globally recognised team of scientists, consultants and engineers, on a wide range of partner projects in a rapidly growing market.

Reporting to the Head of Operations, the Senior Project Manager is accountable for the end‑to‑end delivery of eXmoors Process Development and GMP programmes. The role is central to client satisfaction, cross‑functional execution, and the successful translation of scientific and operational plans into reliably delivered outcomes.

• Manage multiple process development and/or manufacturing projects simultaneously, balancing priorities across a complex portfolio
• Drive end‑to‑end project planning, scheduling, risk management, and resource allocation
• Ensure deliverables are achieved on time, within scope, and within budget, escalating risks proactively to the Head of Operations
• Implement fit‑for‑purpose governance and milestone tracking frameworks

• Align activities across QA, QC, manufacturing, supply chain, regulatory, and development functions
• Ensure internal teams operate in accordance with established project management processes and quality systems
• Support the Hed of Operations with portfolio‑level planning, capacity assessment, and prioritisation

• Ensure all project activities comply with GMP, applicable regulatory guidelines, and internal SOPs
• Support audits, change controls, and deviation management processes as required
• Champion a quality‑first mindset within project teams

• Apply working knowledge of process development, manufacturing, and regulatory pathways to drive informed decision‑making within programmes
• Engage constructively with technical teams across process development, GMP manufacturing, understanding key interfaces and dependencies
• Apply knowledge of technology transfer, scale‑up, or process validation to anticipate risks and shape programme planning
• Maintain awareness of CMO/CDMO business models and client‑service dynamics, ensuring commercial commitments are realistic and deliverable
• Knowledge of legal agreements such as master service agreements, lab services agreements and CDAs

• Apply advanced planning, scheduling, and risk‑mitigation techniques across all programmes
• Utilise project management tools and platforms (e.g. MS Project, Smartsheet, or equivalent) to maintain schedule integrity and stakeholder visibility
• Develop clear scenario planning frameworks to support timely decision‑making under uncertainty

• Identify process improvements to enhance project execution efficiency and client experience
• Provide insights to senior leadership on project risks, opportunities, and resource requirements
• Contribute to the development of eXmoor’s project management capability and ways of working