Senior Clinical Research Manager

The Senior Clinical Research Manager (CRM) provides strategic and operational oversight of the adult medical oncology clinical trial portfolio across six regional satellite locations within the Greater Boston and Southern New Hampshire areas, including Brighton, Milford, Weymouth, Methuen, Foxborough, MA & Londonderry, NH and any future satellite regional campus. The role is responsible for leading and managing the clinical research programs at these sites and for supervising the research staff engaged in the conduct of clinical trials in accordance with Good Clinical Practice, under the direction of the Principal Investigators and the Regional Campus Leadership Team.

In close collaboration with the regional campus medical director, the research physician leads at each campus, and research nursing staff, the Senior CRM is responsible for the implementation and evaluation of both therapeutic and non-therapeutic clinical research activities, ensuring robust regulatory and compliance oversight. The Senior CRM provides direct supervision and professional development for the program’s clinical research staff and is responsible for monitoring and achieving clinical trial performance benchmarks, including protocol and regulatory compliance, patient safety, staff training and development, and financial targets, as defined by Senior Research Leadership and the Regional Campus Leadership Team.

This position’s work location is primarily onsite traveling to DFCI regional sites in Brighton, Milford, Weymouth, Methuen, Foxborough, MA & Londonderry, NH, and any future regional campus location. This role will be up to 1 day remote per week. The selected candidate may only work remotely from a New England state (ME, VT, NH, MA, CT, RI). The individual selected for the position will be required to have regular presence across the regional locations and be available to work onsite at various campuses throughout the work week.

Located in Boston and the surrounding communities, Dana‑Farber Cancer Institute is a leader in life‑changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high‑risk and underserved populations.

We conduct groundbreaking research that advances treatment, we educate tomorrow's physicians, and we work with amazing partners, including other Harvard Medical School‑affiliated hospitals.

• Clinical Research Managers (CRM) are responsible for the oversight of their disease group’s clinical trial portfolio and all related regulatory, compliance and performance metrics requirements.
• The CRM will oversee the processing of protocols through DFCI Institutional Review Board (and other institutions’ IRBs) when appropriate. The CRM will collaborate with the DFCI Clinical Trials Office (CTO), the Office for Human Research Studies (OHRS), and the Office of Data Quality (ODQ) to fulfill local and federal requirements governing human clinical trials.
• The CRM will identify and manage operational, logistical, and regulatory challenges related to the conduct of clinical trials and acts as a leader in overseeing their resolution.
• The CRM will assist the principal investigator in developing the protocol budget, in collaboration with Research Administration and the Grants and Contracts offices. Work with grant managers and other financial managers in the reporting and accounting of these funds.
• Oversees and coordinates the purchase, receipt, inventory and distribution of equipment utilized in the conduct of clinical trials.
• In collaboration with clinical research administration and grant managers, may maintain, monitor and reconcile all study and related grant finances. These may include budget development, expenditure tracking, procurement, salary offset worksheets and staffing.
• Assists the principal investigator in preparing manuscripts for publication.
• The…