Associate​/Scientist Analytical Development, Mass Spectrometry; m​/f​/d

Position: Associate/Scientist Analytical Development, Mass Spectrometry (m/f/d)
Description We are seeking an experienced and highly motivated Scientist with expertise in LC-MS characterization and analytical method development. This is a hands-on, laboratory-based role with responsibilities including LC-MS development, qualification, and routine analysis. The successful candidate will collaborate closely with multidisciplinary teams across Prota Gene and with external pharmaceutical clients to deliver high-quality analytical solutions and support client programs.

Your Responsibilities Perform LC-MS characterization of biologics: prepare samples (SPE, IP, LLE), run chromatography and mass spectrometry experiments, and generate data that supports client programs.

Support lab operation, and the maintenance, qualification, and troubleshooting of LC-MS instrumentation and other laboratory equipment.

Independently design and execute laboratory studies, analyze and interpret data, troubleshoot analytical challenges, and communicate findings through technical reports, presentations, and team discussions.

Maintain accurate and compliant laboratory records, electronic laboratory notebooks (ELNs), experimental protocols, and supporting documentation in accordance with company procedures and quality standards.

Prepare, qualify, and maintain assay reagents, reference standards, controls, and other materials required to support analytical testing activities.

Prepare, review, and present project updates, technical data, and study results to internal teams and external clients.

Continuously expand technical expertise and develop analytical skills to support emerging assays and characterization strategies for biologics, gene therapy, and cell therapy programs.

Collaborate effectively with multidisciplinary teams to ensure the timely delivery of high-quality analytical results and project milestones.

Requirements Bachelor’s degree in Chemistry, Biochemistry, or a related scientific discipline with 3–5 years of relevant laboratory experience, or a Master’s degree with 1–3 years of relevant experience.

Demonstrated hands-on experience with LC-MS analysis of biological samples, including protein extraction and digestion, peptide cleanup and separation, instrument operation, LC-MS acquisition method development, and data analysis is required.

Prior experience in the biotechnology, pharmaceutical, or related life sciences industry is strongly preferred.

Proficiency with Thermo Orbitraps and software is a strong plus.

Working knowledge of biotherapeutic analytical development  (e.g., method qualification and assay transfer) is a plus. Ability to independently plan and execute experiments while managing multiple priorities and maintaining timelines in a fast-paced  environment. Ability to work successfully in both a team/matrix environment as well as independently.

Experience with the analytical characterization of oligonucleotides, ADCs, and AOCs a plus. What we offer

Benefits:
Comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.

Work Environment:
Laboratory-based position in a fast-paced, growth-oriented environment.

Category Operations