Principal Immunoengineer – Translational Human Immunology

Principal Immunoengineer – Translational Human Immunology page is loaded## Principal Immunoengineer – Translational Human Immunology remote type:
On Site locations:
Canada - Burnabytime type:
Full time posted on:
Posted Todayjob requisition :
R-221950##
** Career Category
** Scientific## ##
** Job Description**## Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
** Principal Immunoengineer – Translational Human Immunology**##
** What you will do
** Let’s do this. Let’s change the world. We have an opening for a Principal Scientist on our Large Molecule Discovery group, located at Amgen British Columbia. Our team specializes in the discovery of large molecules and the development of Predictive In vitro Biological Systems to evaluate the efficacy and safety of new candidate molecules.

You will lead translational efforts in protein design with a mission to eliminate or reduce immunogenicity in large molecule therapeutics. This pivotal role bridges experimental immunology and computational science to ensure novel biologics are safe and effective from the outset.##
** What your role will be
*** To embed with our wet-lab teams and lead communication and drive collaboration between the computational data sciences and laboratory research teams.
* Leverage ground-breaking technologies to interrogate adaptive humoral and cellular immune responses
* Design experiments to test and validate novel immunomodulatory methods and compounds
* Develop strategies to direct the adaptive immune response towards desired outcomes
* Collaborate with protein engineers to create, test and optimize novel molecule designs
* Lead external collaborations with academic and industry partners to access emerging technologies in Immunoengineering and AI-driven protein design.
* Monitor and evaluate scientific advances relevant to adaptive immunity and therapeutic engineering to inform strategic R&D decisions.##
** What we expect of you
** We are all different, yet we all use our unique contributions to serve patients. The professional we seek is an innovative leader with these qualifications.
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* Basic Qualifications:

** Doctorate degree and 6 years of relevant experience## OrMaster’s degree and 10 years of relevant experience## Or Bachelor’s degree and 12 years of relevant experience## And4 years of managerial experience directly managing people and/or leadership experience leading teams, projects, programs or directing the allocation of resources
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* Preferred Qualifications:

*** PhD in Immunology, Biomedical Engineering, Vaccinology or Computational Systems Biology.
* Postdoctoral studies in related disciplines; antigen-processing, vaccine design, T and B cell epitope prediction, immune repertoire profiling.
* Hands-on experience with in vitro immunogenicity assays and in silico modeling tools
* Proven track record of integrating laboratory science and state-of-the-art machine learning protein design modeling tools to solve challenging protein design problems
* Experience working in the wet lab or directly with wet lab scientists
* Great communication abilities and meticulous attention to detail, including for written and oral presentation and code documentation
* Broad general interest in modeling complex biological systems
* Ability to drive an end-to-end project including working with…