Bioinformatician, Data Analysis, Cumming School of Medicine

The Cumming School of Medicine invites applications for a Bioinformatician, Data Analysis
. This Full-time Fixed Term position is for approximately 1 year (based on length of grant funding), with the possibility of extension.

This position within the Office of the Associate Dean Research (OADR) and supports the Centre for Advanced Technologies (CAT) and associated CAT core facilities within the Cumming School of Medicine (CSM). The position reports to the Data Scientist and Bioinformatics Manager at ASOC.

CAT is a suite of research core facilities that provides advanced technologies, technical expertise, data generation and analytical support to investigators across a broad range of biomedical and translational research programs. The Bioinformatician provides technical bioinformatics and computational analysis support for data generated through CAT facilities and associated research platforms.

The position supports the analysis of diverse datasets, generated within the CAT suite of core facilities, which may include next-generation sequencing, bulk and single-cell transcriptomics, spatial omics, genomics, proteomics and other high-dimensional molecular datasets. The Bioinformatician applies established bioinformatics tools, computational workflows and analytical approaches to process, analyze, integrate, visualize and interpret research data.

Bioinformatics Analysis and Technical Support:

• Apply and maintain computational workflows for the processing and analysis of biological research data
• Analyze diverse datasets that may include genomic and next-generation sequencing data, bulk and single-cell transcriptomics, spatial omics, proteomics and multi-omic datasets
• Perform appropriate data preprocessing, quality control, normalization, statistical analysis and visualization using established bioinformatics approaches
• Apply existing bioinformatics software, packages and computational methods appropriate to specific research datasets and analytical questions
• Adapt and modify established analytical workflows to accommodate different datasets, experimental designs and project requirements
• Integrate data from multiple experimental platforms or publicly available data repositories where required for assigned analyses

• Work with investigators, research staff and trainees to understand defined research questions and analytical requirements
• Provide technical input regarding appropriate bioinformatics tools, analytical approaches, data requirements and expected analytical outputs
• Conduct assigned analyses, prepare results, figures, visualizations and technical summaries for research teams
• Communicate analytical results and technical considerations clearly to researchers and other members of multidisciplinary project teams
• Identify technical issues that may affect analysis quality or project timelines and communicate these issues to the Bioinformatics Manager and relevant project team members

• Contribute to the development, testing, validation and documentation of new or updated analytical workflows under the direction of the Bioinformatics Manager or appropriate scientific lead
• Contribute to technical improvements to existing analytical workflows based on experience with research datasets and evolving bioinformatics practices
• Maintain current knowledge of bioinformatics tools, analytical methods and relevant developments in genomics, transcriptomics, single-cell analysis, spatial biology, proteomics and other applicable areas
• Participate in testing and implementation of analytical approaches that expand the range of bioinformatics services available through CAT

• Work…