Research Scientist in CRISPR Genomics, Engreitz Lab

Overview

The Laboratory of Jesse Engreitz (Dept of Genetics, BASE Initiative) is seeking a Research Scientist in CRISPR Genomics (Life Science Research Professional
3) to lead large-scale data production projects to understand the genetic basis of heart diseases. The Engreitz Lab is located in the Biomedical Innovations Building on the main campus at Stanford University and is a member of the BASE Initiative in the Betty Irene Moore Children’s Heart Center.

We are looking for a creative and passionate Research Scientist (PhD-level) to lead the next phase of our efforts to systematically perturb the genome to understand genome function and phenotype. The ideal candidate would lead independent projects, design and supervise large-scale CRISPR data generation projects, manage collaborations between the Engreitz Lab and NIH-led consortia, and play a leading role in writing publications and grants.

The Engreitz Lab provides a dynamic, interdisciplinary workplace with unique access to cutting edge technologies and scientific thought, with the potential for widespread recognition of scientific contributions. We value a diversity of values, backgrounds, and approaches to solving problems.

Position type: 2-Year Fixed-Term, with extension possible. For information and recent work, see https://(Use the "Apply for this Job" box below). and .

• Make fundamental discoveries about gene regulation and the genetics of cardiovascular disease
• Together with PI and other lab members, design and execute scientific projects
• Collect comprehensive perturbation datasets to inform genome function and enable training predictive models
• Develop and apply strategies to study enhancers and genes in human cells and mouse models
• Evaluate and recommend new emerging technologies, approaches, and problems
• Supervise, train, and collaborate with other lab members in experimental techniques, scientific design, and other skills
• Design and lead independent projects
• Collaborate with a team of experimentalists and computational biologists
• Create scientifically rigorous visualizations, communications, and presentations of results
• Contribute to generation of protocols, publications, and intellectual property
• Other duties may also be assigned.

• Ph.D. in Genetics, Biology, Biochemistry, Biophysics, Bioengineering, Developmental Biology, or related life science field is preferred. Highly motivated candidates of all levels are encouraged to apply.
• Hands-on experience in cellular genomics, molecular biology, and technology development
• Experience with quantitative data analysis
• Experience with CRISPR targeting ES/iPS cells and/or single-cell technologies a plus
• Experience in multidisciplinary collaborations, management, and/or supervision
• Curiosity in research and creativity in problem-solving
• Strong interpersonal and collaboration skills; outstanding verbal and written communication abilities
• Ability to adapt to and effectively manage changes in a fast paced and dynamic environment
• A passion for science and sense of urgency to find new medicines to benefit patients

Bachelor's degree in related scientific field and four years of relevant work experience; or Master’s degree in a related scientific field and two years relevant experience; or PhD in related science field.

• Comprehensive understanding of scientific principles
• Expert level knowledge and skills in field of science related to the research project
• General computer skills and experience with databases and scientific applications
• Strong analytical skills and excellent judgment
• Ability to work under deadlines with general guidance
• Excellent organizational skills and demonstrated ability to complete detailed work accurately
• Developing project management skills

None.

• Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects
• Occasionally sit, kneel, crawl, reach and work above shoulders
• Rarely…