Senior Scientist

We accelerate the successful discovery, design, and development of human therapeutics by testing on large, lab-grown human organ tissues at massive scale, driving technological advancement at the convergence of novel biology, robotics, and AI. We identify and validate new therapeutic targets and de-risk new therapeutic assets by producing clinically translatable multi-omic data from our proprietary, physiologically-realistic human organ tissues at unprecedented scale, speed, and quality.

This enables us to produce more human data than all clinical trials in the U.S. combined. We’re financially backed by some of the most selective and successful venture funds, and we have already partnered with a majority of the top 10 multinational pharmaceutical companies to discover and develop better, safer drugs and dramatically reduce the burden of animal testing.

This is a full-time, onsite role in San Francisco.

You will lead the development, optimization, and scaling of advanced human tissue models to be deployed within Vivodyne’s automated experimentation platform for therapeutic discovery.

As a Senior Scientist on the Bioengineering team, you will own a scientific program centered around a specific tissue system or disease model, driving projects from early biological hypothesis generation through mature, scalable workflows. You will work cross-functionally with bioengineers, computational biologists, AI scientists, roboticists, hardware engineers, and translational researchers to develop next-generation human tissue platforms that enable deeper understanding of human biology and drug response.

This role requires exceptional experimental rigor, deep technical expertise in complex cell culture systems, strong scientific reasoning, and the ability to make sound, data-driven decisions in ambiguous and fast-moving environments. We are looking for a scientist who combines deep biological intuition with disciplined execution and who consistently designs experiments that produce clear, actionable conclusions.

• Lead development and optimization of complex in vitro human tissue models using primary human cells and advanced 3D culture systems - deep experience in intestine, lung or immuno-biology is a bonus.
• Design, execute, and interpret rigorous experiments with clear success criteria and proper controls to improve tissue phenotype, stability, scalability, reproducibility, and biological relevance.
• Drive mechanistic understanding of tissue behavior through multimodal characterization approaches.
• Troubleshoot difficult experimental problems systematically using first-principles reasoning and quantitative analysis.

• Partner closely with robotics and hardware teams to adapt tissue workflows for automated operation and large-scale experimentation.
• Support transfer of tissue models from exploratory R&D into reliable production-grade workflows.
• Identify sources of experimental variability and implement strategies to improve robustness and reproducibility.
• Contribute to the development of scalable assay and tissue characterization pipelines.

• PhD in bioengineering, cell biology, molecular biology, physiology, developmental biology, genetics, or a related field. A focus on gut, lung or immuno-biology a large plus.
• 2-4 years of industry experience following PhD and/or postdoctoral training in biotechnology, therapeutics, tissue engineering, or related fields.
• Demonstrated record of scientific achievement through high-impact publications, patents, awards, or other evidence of advancing the state of the art in your field.
• Deep…