Manager, Clinical Portfolio Services, Business Operations

Overview

The Manager, Clinical Portfolio Services, Business Operations serves as a strong cross‑functional partner for financial and resourcing planning needs for Clinical Operations, as well as direct support for Clinical Research Organizations (CROs) work order and contract modification processes. This role works closely with the Director, Clinical Portfolio Services, Business Operations and key stakeholders to follow tight financial controls and is responsible for reporting, analytics, project management, and coordination required to drive the business to efficient and effective financial and resource management processes.

• In partnership with FP&A and Suppliers and Study Management, ensure accurate, transparent, and timely financial analyses to support Clinical Operations accruals; clearly articulate financial implications from variances between forecast and actuals and provide retrospective analysis as well as drive forward actions for key business stakeholders. Supports Clinical Development Expertise Areas as needed
• Support Clinical Operations budget, forecast and long‑term planning.
• Complete all required variance analyses for projects. Identify risks in the project forecast and opportunities to improve revenue outlook. Communicate, document and manage these on an ongoing basis.
• Responsible for review of transparency reporting provided by CRO to ensure alignment with operation plan for study.
• Develop and deliver training to support effective financial management processes throughout the Clinical Operations organization. Supports Clinical Development Expertise Areas as needed.
• Manage Purchase Orders (including entry and approval routing) and Change Orders for Clinical Trials.
• Contribute to continuous improvement and maintain a focus on value‑add services relating to resource planning and financial planning.

• Knowledge of clinical operations process, understand concept of clinical trials Phase I-III
• Strong ability to manage and motivate colleagues in a matrix organization
• Strong business acumen
• Strong problem solving and analytical skills
• Sound interpersonal, verbal and written communication skills
• Commitment to and performs consistently high quality work
• Ability to present effectively in a variety of settings
• Ability to successfully work in a ('virtual`) team environment
• Ability to identify and address issues proactively in a timely manner
• Ability to take work independently
• Comfort around senior management; effectively represents capabilities of team

• BA/BS in Operations, Science, Finance or Data Science required.
• 5 years of progressive R&D Business Operations, Sourcing, or Finance/Resourcing roles, with strong analytical and partnering track record.
• Strong experience in Pharma/CRO/Biotech, specifically with pricing models, supplier contracts and internal budget planning
• Strong proficiency in Microsoft Excel (data manipulation) and PowerPoint (leadership presentations)
• Demonstrated experience with Ariba, SAP, or other financial software is not required, but preferred

$ - $

The pay range reflects the full‑time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short‑term incentive award (e.g., bonus or sales incentive) and an annual long‑term incentive award (e.g., equity).

Alnylam's robust Total Rewards package is designed to support your overall health and well‑being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k) with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company‑wide recharge breaks. We also offer generous family resources and leave.

Our commitment to your well‑being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of…