VP, Strategic Planning

The Vice President, Strategic Planning is a senior enterprise leader and key member of the Financial & Strategic Planning leadership team, serving as a strategic partner and trusted advisor to the SVP, Financial & Strategic Planning and executive leadership team. This role is responsible for driving enterprise-wide strategic alignment, execution governance, and portfolio prioritization in support of Alnylam's 2030 strategy.

The Vice President will serve as a highly visible enterprise leader, influencing cross-functional decision-making, driving strategic trade-off discussions, and facilitating executive alignment across complex business issues. Success in this role requires exceptional strategic acumen, executive presence, organizational leadership, and the ability to mobilize leaders across the enterprise to achieve transformative business outcomes. Strategic Planning under this leader will be responsible for Alignment, Timing & Coordination (ATC), the enterprise initiative focused on integrating key projects focused on delivering our 2030 objectives, as well as the Strategic Planning Center of Excellence, which includes the corporate goals process, program management of enterprise initiatives and thought partnership across the company.

As the leader of Alignment, Timing & Coordination (ATC), the VP will establish the operating framework that enables effective execution of the company's most critical strategic priorities. The role will ensure enterprise investments, resources, and change initiatives are aligned with strategic objectives, business performance expectations, and organizational capacity.

• Lead the enterprise Alignment, Timing & Coordination (ATC) framework to ensure successful execution of Alnylam's strategic priorities and long-range objectives.
• Partner with the Executive Leadership Team to drive alignment on enterprise priorities, resource allocation, sequencing decisions, and strategic trade-offs.
• Provide enterprise level visibility across the strategic initiative portfolio, including progress, dependencies, risks, resource demands, and organizational impact.
• Anticipate emerging business risks, organizational capacity constraints, and execution challenges, proactively recommending mitigation strategies and executive actions.
• Lead enterprise governance processes, including executive reviews, portfolio prioritization, strategic performance monitoring, and decision-making forums.
• Drive organizational alignment and transparency through effective executive communications, governance forums, and enterprise-wide engagement strategies.
• Lead enterprise discussions regarding prioritization, sequencing, resource allocation, execution capacity, and organizational readiness across strategic initiatives. Identify interdependencies, competing priorities, timing conflicts, and capacity constraints that may affect the strategic portfolio.
• Recommend portfolio-level trade-offs and coordination approaches that optimize enterprise effectiveness and support achievement of strategic objectives.
• Partner with initiative sponsors and leaders to ensure alignment with enterprise priorities, governance expectations, and approved resource plans.
• Develop frameworks and reporting that provide leadership with consistent visibility into initiative demand, portfolio health, and organizational capacity.

• Translate enterprise strategy into actionable operating priorities, multi-year roadmaps, and measurable business outcomes.
• Partner across Finance, Commercial, R&D, Technical Operations, Corporate Functions, and other key stakeholders to ensure strategic initiatives are integrated into planning and resource allocation processes.
• Lead development of executive-level analyses, strategic recommendations, investment frameworks, and business cases that inform key enterprise decisions.
• Monitor enterprise performance and strategic initiative outcomes, identifying opportunities to optimize execution, resource deployment, and organizational effectiveness.
• Provide thought leadership on emerging trends, market dynamics, and organizational capabilities that may impact achievement of strategic objectives.

• Serve as a key member of the Financial & Strategic Planning Leadership Team, contributing to the overall direction, strategy, and operating model of the function.
• Act as a trusted advisor to senior leaders, providing strategic counsel and objective perspectives on complex business…