Clinical Lead, Early Clinical and Experimental Therapeutics

* Participate in designing the early development plan and overall ECET plan for the different steps of clinical development, integrating into to the overall development strategy in collaboration with the responsible Therapeutic Area in research and development.
* Design safe, rapid and informative First-In-Human studies including First In Patients, natural history, experimental model validation, mechanistic and signal seeking, streamlined Proof-of-Mechanism as well as Proof-of-Concept studies providing robust data for early Go/No Go decisions and other pharmacokinetic studies.
* Supervise the execution and ensure close medical monitoring.
* Review, interpret results, and author ECET-related clinical documentation, including informed consent forms, clinical protocols, study reports; some abstracts and/or manuscripts; clinical pharmacology or ECET components of investigator brochures, regulatory documents.
* Interact effectively with managers from various disciplines; serve as expert and internal consultant on assigned area and liaises with partners on projects.
* Participate in the dose selection for First-In-Human studies, drive Go/No Go decisions when needed.
* Ensure an adequate follow-up of studies and project timelines.
* Present data at appropriate meetings (inside or outside Sanofi).
* Present data at appropriate meetings (inside or outside Sanofi).
* Spokesperson of TMU and Clinical Patient Sciences; requires a committed and enthusiastic person to emphasize the strengths of the position and a positive, collaborative mindset.
* Take an active part in the scientific challenges involved in early clinical development, which require a scientifically inquisitive, energetic and proactive person.
* Ensure Clinical Trial standards are maintained at the site and in cooperation with the other clinical functions. Requires excellent communication skills and the implementation of an appropriate process for communication.
* Ensure high quality documents, requiring strong writing and communication skills.
* Manage aggressive timelines effectively through cross-functional planning.
* Decision Making Authority:
Make front-line decisions on protocol design, execution, dose escalation and safety, information for Regulatory authorities.
* Knowledge and mindset in translational research.
* Experience in the conduct of late phase clinical trials.
** Education and Training**:
* Advanced degree: M.D. or M.D./Ph.D with at least 1-5 years of research experience
* Postgraduate residency training; laboratory research in industry or academia
* Broad biomedical knowledge base
* Knowledge and mindset in translational research
* Able to acquire and apply new technical skills
** Soft and technical skills**:
* Very good communication skills (verbal and written) for interactions across functional areas and for interactions with key regulatory agencies
* Demonstrated capability to challenge decision and status quo with a risk-management approach
* Ability to work within a matrix organization, within CPS, TMU, R&D and beyond e.g. Medical.
* International/ intercultural working skills
* Open-minded to apply new digital and/or AI-driven solutions.
* Bring the miracles of science to life alongside a supportive, future-focused team.
* Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
* Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
* Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.
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