Senior Global Medical Affairs Lead, Cardiovascular & Renal; CVRM

Location:
Boston (preferred), Gaithersburg

Hybrid: 3 days a week on site

Reporting to the Global Medical Head, the Senior Global Medical Affairs Lead, Cardiovascular & Renal is a highly experienced Medical Affairs leader with proven vision and impact. This individual develops and leads bold medical strategies within the CVRM (Cardiovascular, Renal & Metabolism) therapy area — spanning hypertension, chronic kidney disease (CKD) and heart failure — expertly guiding cross-functional and cross-regional teams to deliver and exceed ambitious goals.

The Senior GMAL's influence is enterprise-wide—shaping global medical agendas through Global Medical Team, Global Product Team, and Disease Area Team leadership, and deep partnership with Medical and Commercial functions in markets and regions worldwide.

• Strategy & Transformation:
  The Senior GMAL designs and leads the implementation of product and disease area strategies, as well as ambitious practice change initiatives, at a global level. This requires a deep understanding of healthcare system pathways, regulatory landscapes, market access, and competitive dynamics. The Senior GMAL consistently delivers innovative, disruptive solutions to shape markets, challenges status quo thinking, and uses digital, AI and data capabilities to identify opportunities, preparing for launch and life cycle management.
• Medical Evidence Leadership:
  Senior GMALs lead the evidence generation strategy—demonstrating advanced experience in clinical research, interventional trials (Phases 2–4), and real-world evidence (RWE) programs. They shape and drive groundbreaking clinical trials, registries, and RWE studies aligned with brand, access, and practice-changing objectives. They guide the optimisation, communication, and strategic roll-out of data across scientific platforms, ensuring AstraZeneca delivers differentiated evidence that supports the needs of regulatory, payer, and healthcare providers.
  
  Clinical research, patient outcomes expertise, and deep understanding of treatment protocols underpin their ability to address evolving evidence requirements.
• Advanced Scientific & Digital Engagement:
  The Senior GMAL blends scientific expertise with strong digital acumen. They leverage digital health, AI, advanced analytics, and data platforms to transform evidence communication, personalize stakeholder engagement, and enhance patient outcomes. They are the voice of medical—crafting compelling narratives, driving digital dissemination of evidence, and ensuring accurate, impactful, and compliant scientific communications.
• Guiding and Influencing Stakeholders:
  With significant expertise in internal and external engagement, the Senior GMAL builds and sustains powerful relationships across the healthcare ecosystem—including global and regional KOLs, professional societies, regulators, payers, patient organizations, technology innovators, and health systems. Their credibility and influence enable them to mobilize support for medical strategy, evidence generation, and healthcare change initiatives. They mentor and guide cross-functional teams, championing scientific leadership and strategic collaboration.
• Regulatory Insight & Compliance:
  The Senior GMAL possesses keen regulatory understanding and ensures clinical trial and evidence generation initiatives are designed for both scientific and regulatory success. They anticipate evolving regulatory and payer requirements for evidence, ensuring high quality, compliant data generation and communication at every stage.

• Advanced degree in a relevant discipline required (MD, PhD, PharmD
• At least 5 years of relevant experience in the pharmaceutical industry (Medical, Marketing, R&D,…