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IT: Senior IT & Cybersecurity Architect

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Nanobiosym
Full Time position
Listed on 2025-12-28
Job specializations:
  • IT/Tech
    Cybersecurity, Systems Engineer, Cloud Computing, Network Security
Salary/Wage Range or Industry Benchmark: 120000 - 150000 USD Yearly USD 120000.00 150000.00 YEAR
Job Description & How to Apply Below

Location: Cambridge, MA

Company: Nanobiosym

Job Summary

Nanobiosym is an award-winning company at the forefront of nanotechnology, physics, and biomedicine. Based in Cambridge, MA and founded by an MIT/Harvard alum, we are building next-generation tech solutions for healthcare.

We are looking for a Senior IT & Cybersecurity Architect to build out and upgrade end to end IT infrastructure—from secure networks and virtualized environments to cloud security and endpoint management. This is an on-site, hands-on role for someone who can design, implement, and proactively manage a highly secure, high-performance IT environment, while working closely with executive leadership to align technology with business goals.

Responsibilities
  • Design, implement, and manage secure, scalable networks (LAN/WAN, VLANs, VPNs, SD-WAN) and segmentation strategies.
  • Deploy and maintain virtualization infrastructure (VMware, Citrix) and containerized environments (Docker, Kubernetes).
  • Architect and manage Zero Trust and zero/thin client environments for secure endpoint access.
  • Configure and manage firewalls, access controls, and monitoring systems to ensure 24/7 security and availability.
  • Lead user and VM provisioning
    , device management, and endpoint security across Windows and Linux systems.
  • Implement and oversee AWS cloud security
    , including IAM, VPCs, S3, and centralized logging.
  • Conduct regular risk assessments, propose security improvements, and lead incident response when needed.
  • Develop documentation (network diagrams, SOPs, access policies) and enforce compliance with standards (NIST, ISO 27001).
  • Collaborate with leadership to define IT/security roadmaps, manage priorities, and communicate risks/tradeoffs.
  • Evaluate and onboard vendors, tools, and services aligned with infrastructure needs.
Required Qualifications
  • PhD or Master's degree in Computer Science, Information Security, Engineering, or a related field.
  • 7+ years of hands-on experience in IT infrastructure, cybersecurity architecture, and systems engineering.
  • Proven experience designing and managing virtualized environments (VMware, Citrix) and containerized systems (Docker, Kubernetes).
  • Strong understanding of networking principles (TCP/IP, DNS, DHCP) and practical experience configuring firewalls, VLANs, VPNs, and SD-WAN
    .
  • Hands-on expertise in implementing Zero Trust architecture
    , zero/thin client infrastructure
    , and securing air-gapped or segmented environments.
  • Deep experience with user provisioning, identity and access management (IAM), and endpoint control across Windows and Linux systems.
  • Proficiency in securing and operating AWS environments
    , including VPC design, IAM roles, encryption, and monitoring (Cloud Watch, Guard Duty).
  • Familiarity with infrastructure automation tools such as Power Shell, Bash, Terraform, or Ansible.
  • Experience with SIEM platforms, EDR tools
    , and log aggregation for detection and response (e.g. Splunk, Logz.io, Sentinel One, etc.).
  • Solid grasp of cybersecurity frameworks and compliance standards such as NIST CSF, ISO 27001, HIPAA
    , and awareness of FDA-related frameworks (e.g. IEC 62304).
  • Ability to work autonomously in a high-trust environment, define best practices, and build systems from the ground up
    .
  • Excellent documentation and communication skills
    , with the ability to clearly articulate technical decisions, risk tradeoffs, and system architecture to non-technical leadership (CEO, legal, operations, etc.).
  • DOD Compliance and Security Clearance preferred.
Preferred Qualifications
  • Certifications:

    CISSP, CISM, CCNP, AWS Security Specialty
    , or similar.
  • Familiarity with scripting/automation (e.g. Power Shell, Python, Terraform, Ansible).
  • Experience working in regulated industries (biotech, pharma, healthcare).
  • Knowledge of compliance frameworks:
    NIST CSF, ISO 27001, IEC 62304, HIPAA
    .
  • Exposure to OT, IoT, or LIMS environments is a plus.
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Position Requirements
10+ Years work experience
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