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Associate Director​/Director, Medicinal Chemistry - Cambridge, MA

Job in Cambridge, Middlesex County, Massachusetts, 02140, USA
Listing for: Recludix Pharma
Full Time position
Listed on 2026-01-03
Job specializations:
  • Pharmaceutical
    Drug Discovery, Medicinal Chemist
Salary/Wage Range or Industry Benchmark: 170000 - 240000 USD Yearly USD 170000.00 240000.00 YEAR
Job Description & How to Apply Below

Associate Director/Director, Medicinal Chemistry

Recludix Pharma is a precision medicine company unlocking a powerful new class of small molecule therapeutics targeting SH2 domains — a previously undruggable family of intracellular proteins regulating immune signaling. Founded by pioneers in kinase drug discovery, Recludix is developing first-in-class therapies with potential to transform treatment in inflammatory disease and beyond.

Recludix is advancing multiple pipeline programs, including a STAT6 inhibitor — one of the most exciting targets in immunology — with additional programs moving rapidly toward the clinic. This is a unique opportunity to join a fast-growing company with a truly novel platform, strong scientific leadership, and a bold vision for the future.

Job Summary:

We are seeking a medicinal chemist with experience in synthetic chemistry and drug discovery. A successful candidate will be skilled in applying modern multi-parameter medicinal chemistry techniques and performing in-depth data analyses. We are seeking candidates who are self-motivated and able to work both independently and as part of a multi-disciplinary team to drive success.

Responsibilities:
  • Contribute to the medicinal chemistry strategy and tactics
  • Drive programs forward by applying modern multi-parameter optimization and data analysis techniques in a creative way
  • Contribute high impact small molecule designs
  • Effective management of CRO synthetic chemistry collaborations
Qualifications:
  • Ph.D. with 7+ years or B.A./M.S. with 12+ years of relevant experience and proven success using a rigorous and creative approach to scientific problem solving
  • Strong track record of successfully driving drug discovery programs through lead optimization
  • A thorough knowledge of synthetic organic chemistry, DMPK, pharmacology and pre-formulation; SBDD experience is a plus
  • Outstanding communication and interpersonal skills
Further Information:

Salary range: $170,000 – $240,000

In addition to a competitive compensation package with stock options, Recludix Pharma also offers a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, life insurance, disability insurance and a 401(k) plan/match.

Recludix Pharma is proud to be an Equal Opportunity employer. We do not discriminate based upon race, religion, color, national origin, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender, gender identity, gender expression, transgender status, sexual stereotypes, age, status as a protected veteran, status as an individual with a disability, or other applicable legally protected characteristics. Recludix Pharma is committed to providing reasonable accommodations for candidates with disabilities in our recruiting process.

If you need any assistance or accommodations due to a disability, please let us know at  .

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to  Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions.

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Position Requirements
10+ Years work experience
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