Senior Principal Scientist, Lab Head Medicinal Chemistry

Senior Principal Scientist, Lab Head Medicinal Chemistry

Location:

Cambridge, MA About the Job

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.

Integrated Drug Discovery (IDD) is the small molecule drug discovery platform within Sanofi. IDD is an international, interdisciplinary group that spans medicinal chemistry, structural biology, screening, biochemistry, biophysics, cellular pharmacology, delivery technologies, sample management and more.

Our vision is to deliver valuable, high quality synthetic drugs of varying modalities to improve the lives of patients. Our mission is to provide innovation and key enabling technologies to drive the discovery of synthetic small molecules and emerging synthetic modalities as drug candidates in the Sanofi Research Portfolio; to deliver high quality science and innovative approaches to drug discovery, and to perform as a highly collaborative flexible and forward‑looking organization with broad impact across the Sanofi pipeline.

We are seeking a dynamic and experienced medicinal chemist to join our Cambridge, MA‑based team as a Senior Principal Scientist.

We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people’s lives. We’re also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started? We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams.

With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

• The successful candidate is a proven, experienced team leader with a track record of success in medicinal chemistry and multidisciplinary drug discovery.

• A Senior Principal Scientist is responsible for applying deep scientific expertise and judgment to initiate, design, and direct medicinal chemistry in support of research goals.

• Is an expert in analyzing, interpreting and communicating scientific content to teams and stakeholders.

• Demonstrates continuous growth in depth and breadth of scientific knowledge and understanding of strategic goals of group, team and company.

• Successfully works as an impactful contributor, and as a leader of project teams and transverse initiatives; is an experienced and supportive manager and mentor of other medicinal chemists.

• Has an established and growing reputation in the external scientific community through high impact publications, productive scientific collaborations and active participation in conferences.

• PhD in Organic/Medicinal Chemistry with 7+ years of experience in a pharmaceutical/biopharmaceutical environment.

• Or Master’s degree in Organic Chemistry with 9+ years of experience in a pharmaceutical/biopharmaceutical environment.

• Or Bachelor’s degree with 12+ years of experience in a pharmaceutical/biopharmaceutical environment.

• Exceptional technical skills and demonstrated ability to work and thrive in a collaborative cross‑functional team setting; proven ability to analyze complex data sets, draw conclusions, and design follow‑on experiments.

• Experience in all phases of the small molecule discovery process from hit  candidate nomination.

• Demonstrated track record of intellectual contributions in drug discovery as evidenced by impactful peer‑reviewed publications, presentations, patents, and project achievements.

• Demonstrated success leading multidisciplinary drug discovery projects from conception through key milestones.

• Proven track record mentoring and developing junior scientists with measurable impact on team performance and individual career growth.

• Experience working with CROs and external collaborators.

• Comfortable and efficient in fast moving complex global environment.

• Bring the miracles of science to…