Scientist, Cancer Immunology Discovery

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it.

You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more

The Oncology Thematic Research Center at BMS is a key research and early development engine, responsible for the discovery and development of novel oncology therapeutics for patients. Centered at our state-of-the-art research sites in Cambridge and Seattle, scientists focus on novel targets and pathways for tumors that are refractory to current therapies. With a deep understanding of the causal human biology, we are able to leverage our multiple modality platforms to best match the modality to the mechanism and desired outcome.

We are a fully integrated drug discovery through translational and early clinical development organization which exploits state-of-the-art in vitro, in vivo and ex-vivo models of Cancer biology and Immuno-oncology to identify and validate targets. We partner closely with colleagues in Translational Medicine, Informatics and Predictive Sciences and Early Clinical Development to generate biomarker and patient enrichment hypotheses to enable efficient decision making in early clinical trials.

We are optimally positioned to complement the world-class translational expertise, biology and leading academic research centers in the area.

Our Bristol Myers Squibb research site in Cambridge Crossing will help us continue to deliver on our mission, positioning the company and our scientists in the heart of a vibrant ecosystem of world-class science, innovation, and business opportunities.

• Designs and executes experiments independently, troubleshoots as needed, interprets and discusses data, with accurate, timely and detailed record-keeping
• Performs laboratory work related but not limited to tissue culture, multi-parametric flow cytometry, western blot, immune cell culture using activation/expansion/exhaustion assays, proliferation and tumor killing assays, 2D/3D co-culture activity assays, ELISA, Luminex, processing of DNA/RNA/protein.
• Accurate and detailed record-keeping.
• Presents data in project meetings and department meetings.
• Collaborates with rest of biology team members as well as other functional area leads e.g. protein purification, in vivo pharmacology, DMPK, informatics.
• Utilizes excellent communication and interpersonal skills.

• Bachelor's Degree – 5+ years of academic and / or industry experience
• Master's Degree – 3+ years of academic and / or industry experience
• Ph.D. or equivalent advanced degree in the Life Sciences – No experience necessary

• Extensive expertise and a proven track record in cancer immunology or immunology research, with industry experience in oncology drug discovery; alternatively, a Ph.D. with a strong publication record in top-tier peer-reviewed journals
• Strong understanding of T cell biology, vascular, myeloid, and stromal biology
• Experience in the design, development, and optimization of high-throughput cell-based assays for TCE activity and multispecific biologics
• Proficient in the use of expression modulation tools (e.g., over-expression, CRISPR, RNAi)
• Extensive knowledge of flow cytometry platforms (e.g., BD, Cytek Aurora, iQue)
• Experience with automation systems (e.g., Tecan, Integra)
• Proficiency with imaging platforms (e.g., Incucyte, Opera Phenix)
• Familiarity with data mining using public datasets and platforms (e.g., Dep…