Senior Research Associate, Cardiometabolic Discovery

Company Summary

Quotient Therapeutics Ltd is a privately held, early‑stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.

The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS).

We are an equal opportunity employer.

We are seeking a motivated and creative Senior Research Associate to join our team focused on performing in vitro studies to characterize novel somatic variants in the context of Cardiometabolic disease. This role requires a strong background in life sciences to execute experiments that investigate somatic variant function to validate potential drug targets. The position involves a combination of hands‑on lab work, data analysis, and scientific communication to ensure a target's potential benefit for a disease.

The successful candidate will be a self‑starter, able to thrive in a fast‑paced, action‑oriented team environment.

• Perform a variety of laboratory experiments, including cell‑based assays, molecular biology techniques, and sometimes in‑vivo studies, to validate new targets and test drug candidates
• Utilize techniques such as RNA purification, qPCR, ELISA and Western blotting to analyze cellular and molecular responses
• Assist in the design and optimization of research protocols to validate therapeutic targets
• Collect, analyze, and interpret scientific data, with a strong ability to use tools like Excel and Graph Pad Prism
• Maintain a detailed and up‑to‑date electronic lab notebook and write high quality experimental protocols
• Work in a team‑oriented environment, sharing findings and collaborating with other scientists

• Master’s degree in life sciences, biotechnology, biology, or related field with 0‑2 years of relevant experience in industry
• Bachelor’s degree in life sciences, biotechnology, biology, or related field with 2‑4 years of relevant experience in industry
• Hands‑on experience with cell culture, molecular biology and protein techniques (academic or industry settings)
• Preferred experience in organoid/spheroid primary cell culture systems with steatosis and fibrosis readouts
• Ability to manage multiple tasks, work independently, and thrive in a collaborative team environment
• Familiarity with electronic lab notebooks (ELNs) or related data‑management tools
• Must possess a high degree of flexibility and adaptability to evolving job requirements and priorities

Flagship is an experiment in institutional, entrepreneurial, and innovation practiced in the context of a small company with an insurgent mindset. We are seeking individuals with an entrepreneurial spirit, strong communication skills, and comfort in working in and contributing to a dynamic and cross‑functional team environment.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, we encourage you to apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. The level of the role will be commensurate with the education and years of experience of the identified candidates.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Flagship Pioneering and its affiliated…