Scientific Director, Metabolite Profiling Core Facility

SCIENTIFIC DIRECTOR Posting Description

Responsibilities include overseeing and further developing the operation of a state-of-the-art facility consisting of targeted and untargeted metabolomics and lipidomics platforms using high-resolution, accurate‑mass, liquid chromatography mass spectrometry (LC/MS); collaborating with and advising scientists at KI, MIT, Whitehead Institute, and external institutions on developing and applying LC/MS‑based metabolomic/lipidomic experiments to advance the research; consulting on experimental design, analyzing and interpreting metabolomic/lipidomic data, and developing new LC/MS‑based assays as projects dictate;

participating in grant writing and manuscript preparation and on the acquisition of new equipment to expand and advance scientific applications; and performing other duties as assigned.

Required:

Ph.D. in biological/physical sciences or a related discipline; a minimum of four years of research experience, preferably in a biological/biomedical setting; comprehensive understanding of quantitative methods in mass spectrometry and metabolomics, including instrument operation, sample preparation, and data analysis; experience with lipidomics or willingness/ability to learn; strong communication, troubleshooting, and problem‑solving skills; ability to collaborate with scientists to consult on experimental design, data analysis, and interpretation;

supervisory experience; and ability to work as part of a team.

Preferred:
Working knowledge of Orbitrap systems and accompanying software, understanding of the use of stable isotopes in tracing experiments, and broad knowledge of high‑resolution accurate‑mass data analysis software.

12/12/2025